WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Progressive inflammatory disease of the arterial wall characterized by lipid accumulation, immune cell infiltration, and fibrous plaque formation. In the metallomics framework, atherosclerosis sits at the convergence of three interacting systems: heavy metal toxicity, g…
A neurodevelopmental condition affecting approximately 1 in 36 children (US CDC 2023 estimate), characterized by differences in social communication, restricted interests, and repetitive behaviors. From a metallomics perspective, ASD presents a compelling convergence of…
Bifidobacteriaceae is the family containing bifidobacterium and related genera (alloscardovia). It is the dominant family in the healthy infant gut and a significant commensal family in adults. Family-level depletion is documented in ASD (marked reduction of Actinobacte…
Bifidobacterium adolescentis is a Gram-positive, obligate anaerobic species within the phylum Actinobacteria and the dominant Bifidobacterium species in the adult human gut. It is a specialist degrader of resistant starch and dietary fiber, producing acetate and lactate…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
A progressive loss of kidney function affecting approximately 850 million people worldwide (10–14% of adults), causing 1.2 million deaths annually. CKD is unique among diseases in this wiki because it occupies both sides of the metal-disease equation: heavy metals (Cd, …
The co-occurrence of multiple diseases in the same individual at rates exceeding chance. Comorbidity patterns are a central puzzle in medicine -- why do IBD patients develop CVD? Why does PCOS cluster with T2D? Why do neurodegenerative diseases associate with depression…
iron occupies a unique position among dietary metals: it is both an essential nutrient and a selective pressure that shapes the gut microbial ecosystem. The form, quantity, and bioavailability of dietary iron determines which microbes thrive and which are competitively …
Every meal delivers metals to the gut lumen — essential minerals, trace elements, and contaminants alike. These metals do not passively transit the GI tract. They actively reshape the microbial ecosystem, selecting for metal-tolerant organisms, enabling virulence in met…
Exogenous chemicals that interfere with hormone synthesis, secretion, transport, binding, or elimination, mimicking or blocking endogenous hormones at physiologically relevant concentrations. In the metallomics-microbiome framework, endocrine disruptors occupy a critica…
Erysipelotrichaceae is a family within the phylum Firmicutes that has drawn increasing attention for its consistent enrichment in metabolic disorders. Members of this family are Gram-positive, obligate anaerobes found throughout the mammalian gastrointestinal tract, whe…
The community of trillions of microorganisms — bacteria, archaea, fungi (mycobiome), viruses, and bacteriophages — inhabiting the human gastrointestinal tract, with the highest density in the colon (~10¹¹ cells/g). The gut microbiome encodes 100–150 times more genes tha…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
An umbrella term for metallic elements with relatively high density (conventionally 5 g/cm3), many of which are toxic to biological systems at low concentrations. This wiki uses "heavy metals" broadly to encompass both strictly toxic metals and essential trace metals th…
--- title: Hungatella type: entity subtype: microbe created: 2026-04-10 updated: 2026-04-16 lastsubstantiveupdate: 2026-04-16 sources: [altinok-dindar-2023-gut-microbiota-breast-cancer-diet, qin-2024-consistent-microbiome-signatures-old-young-onset-crc, zhang-2025-gut-v…
Sustained elevation of systemic blood pressure, affecting an estimated 1.3 billion adults worldwide and the leading modifiable risk factor for cardiovascular disease, stroke, and chronic kidney disease. The gut microbiome-blood pressure axis has emerged as a major resea…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
--- title: Intestinibacter type: entity subtype: microbe created: 2026-04-10 updated: 2026-04-16 lastsubstantiveupdate: 2026-04-16 sources: [dai-2024-gut-microbiota-cvd-bidirectional-mr, xiang-2023-host-gene-microbiome-crc-mr, wu-2017-metformin-gut-microbiome-t2d-nature…
Lactobacillaceae is the family containing the genus lactobacillus and related genera. It is the dominant family in the healthy vaginal microbiome and a significant family in the gut. Family-level depletion is reported across schizophrenia szeligowski 2020 gut microbiome…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
--- title: Oxalobacter type: entity subtype: microbe created: 2026-04-10 updated: 2026-04-16 lastsubstantiveupdate: 2026-04-16 sources: [duan-2020-gut-microbiota-heavy-metal-probiotic-strategy, zhang-2022-causal-gut-microbiome-cvd-mr, dai-2024-gut-microbiota-cvd-bidirec…
Paraprevotella is a genus of obligate anaerobic, Gram-negative bacteria in the family Prevotellaceae, related to prevotella. It is a gut commensal with emerging associations across neuropsychiatric and reproductive conditions. - Schizophrenia: Altered in gut-brain axis …
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. In the context of this wiki, probiotics are relevant both as therapeutic agents for metal-related diseases and as mediators of gut metal microbiome interactions. Their …
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
A genus of Gram-negative, crescent-shaped, strictly anaerobic bacteria found in both the oral cavity and the gastrointestinal tract. Selenomonas species are characterized by their distinctive morphology -- a curved rod with a tuft of flagella arising from the concave si…
A genus of Gram-positive facultative anaerobes that occupy niches ranging from benign commensals (dental plaque, skin) to acute pathogens (pharyngitis, impetigo, invasive disease). Streptococci are uniquely manganese-dependent for catalytic scavenging of reactive oxygen…
The primary androgen in human biology, testosterone sits at a critical intersection in WikiBiome's framework: it is both regulated by the gut microbiome and disrupted by heavy metals, making it a node where environmental metal exposure, microbial ecology, and endocrine …
A gut microbiome-derived metabolite that has emerged as one of the strongest microbial biomarkers for cardiovascular disease risk. TMAO exemplifies how microbial metabolism of dietary nutrients can generate systemically toxic products -- a fundamentally different paradi…