Interventions0 sources
Autoimmune Protocol (AIP) Diet for Hashimoto's Thyroiditis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Search: “autoimmune”
Ranked matches across titles, topics, categories, and article introductions.
42 records in this view
Microorganisms13 sources
Alistipes
A Gram-negative, obligate anaerobic genus within the Bacteroidetes phylum (family Rikenellaceae). Alistipes occupies a complex and context-dependent role in the gut ecosystem — some species carry well-documented anti-inflammatory properties, while the genus is paradoxic…
Host defenses3 sources
Autoimmunity
Autoimmunity occurs when the immune system attacks the body's own tissues. What has emerged over the past two decades is that the gut microbiome is not merely associated with autoimmune disease -- it is a mechanistic driver of immune tolerance breakdown. Metals add a se…
Microorganisms3 sources
Bifidobacterium adolescentis
Bifidobacterium adolescentis is a Gram-positive, obligate anaerobic species within the phylum Actinobacteria and the dominant Bifidobacterium species in the adult human gut. It is a specialist degrader of resistant starch and dietary fiber, producing acetate and lactate…
Microorganisms6 sources
Butyricimonas
A Gram-negative, obligate anaerobic genus within the Bacteroidetes phylum (family Odoribacteraceae). Despite its relatively recent characterization, Butyricimonas has gained significant attention as a member of the protective butyrate-producing consortium that is consis…
Microorganisms3 sources
Butyrivibrio
Butyrivibrio is a genus of Gram-positive, obligate anaerobic bacteria within the family Lachnospiraceae (phylum Firmicutes). Originally characterized as a dominant fiber-fermenting genus in the rumen, Butyrivibrio species are also found in the human colon where they con…
Diseases8 sources
Celiac Disease
Celiac disease is a chronic autoimmune condition triggered by dietary gluten (gliadin proteins from wheat, barley, and rye) in genetically susceptible individuals (HLA-DQ2/DQ8, carried by ~30-40% of Europeans but penetrant in only ~1% of carriers). Gluten exposure cause…
Microorganisms5 sources
Collinsella
A genus of Gram-positive, obligate anaerobic bacteria within the Actinobacteria phylum (family Coriobacteriaceae) that has emerged as a consistent pathobiont enriched in cardiometabolic and autoimmune diseases. C. aerofaciens is the most studied species, with establishe…
Diseases15 sources
Crohn's Disease
A chronic, relapsing-remitting inflammatory bowel disease (IBD) characterized by transmural inflammation of the gastrointestinal tract, most commonly affecting the terminal ileum and colon but capable of involving any segment from mouth to anus zhang 2017 intestinal mic…
Diseases8 sources
Dermatitis Herpetiformis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Microorganisms7 sources
Dorea
A Gram-positive, obligate anaerobic genus within the lachnospiraceae family (Firmicutes phylum). Dorea occupies a mixed role in the gut ecosystem -- while it is a core member of the healthy human microbiome, several species are consistently enriched in autoimmune and ne…
Microorganisms4 sources
Erysipelotrichaceae
Erysipelotrichaceae is a family within the phylum Firmicutes that has drawn increasing attention for its consistent enrichment in metabolic disorders. Members of this family are Gram-positive, obligate anaerobes found throughout the mammalian gastrointestinal tract, whe…
Microorganisms11 sources
Eubacterium rectale
Eubacterium rectale (recently reclassified as Agathobacter rectalis) is a Gram-positive, strictly anaerobic, non-spore-forming bacterium that belongs to Clostridium cluster XIVa within the lachnospiraceae family. It is one of the most abundant butyrate producers in the …
Microorganisms5 sources
Fusobacterium
A Gram-negative, obligate anaerobic bacterium that has emerged as the most consistently CRC-associated microorganism in human gut microbiome studies. F. nucleatum is the primary species of concern, originally a commensal of the oral cavity that translocates to colorecta…
Interventions8 sources
Gluten-Free Diet
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Diseases10 sources
Graves' Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms3 sources
Gut-Thyroid Axis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases15 sources
Hashimoto's Thyroiditis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases4 sources
Hepatitis
Hepatitis (liver inflammation) encompasses viral (HBV, HCV, HAV), autoimmune, alcoholic, and toxin-induced forms. In the WikiBiome framework, the gut-liver axis is central — portal blood delivers gut-derived microbial products (LPS, bacterial DNA) directly to the liver …
Microorganisms6 sources
Lactococcus
Lactococcus lactis is a Gram-positive, facultatively anaerobic, lactic acid bacterium best known as the workhorse of the dairy fermentation industry. It holds GRAS (Generally Recognized As Safe) status and has emerged as a versatile platform for probiotic and therapeuti…
Diseases5 sources
Multiple Sclerosis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms9 sources
NF-kB Signaling Pathway
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) is a family of transcription factors that regulate inflammation, immune responses, cell survival, and proliferation. NF-kB is a convergence point where metal toxicity, pathogen signaling, and chronic…
Metals143 sources
Nickel
A transition metal occupying a central position in this wiki's evidence base. Nickel is toxic and carcinogenic to humans, yet an essential cofactor for pathogen virulence enzymes. It is the most frequent contact allergen worldwide and drives a wide spectrum of systemic …
Microorganisms12 sources
Odoribacter
Odoribacter splanchnicus is a Gram-negative, obligate anaerobic bacterium belonging to the family Odoribacteraceae within the phylum Bacteroidota (formerly Bacteroidetes). It is a commensal resident of the human colon recognized primarily as a producer of short chain fa…
Other0 sources
Oxalobacter
--- title: Oxalobacter type: entity subtype: microbe created: 2026-04-10 updated: 2026-04-16 lastsubstantiveupdate: 2026-04-16 sources: [duan-2020-gut-microbiota-heavy-metal-probiotic-strategy, zhang-2022-causal-gut-microbiome-cvd-mr, dai-2024-gut-microbiota-cvd-bidirec…
Diseases5 sources
Pancreatitis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Microorganisms8 sources
Parabacteroides
A Gram-negative, obligate anaerobic genus within the Bacteroidetes phylum, closely related to bacteroides fragilis. The best-characterized species, P. distasonis, has emerged as a key anti-inflammatory commensal with significant roles in bile acid metabolism and metabol…
Microorganisms7 sources
Parasutterella
Parasutterella excrementihominis is a Gram-negative, obligate anaerobic bacterium within the Betaproteobacteria class that has gained attention as an emerging biomarker across metabolic, inflammatory, and endocrine conditions. Despite its relatively recent characterizat…
Microorganisms9 sources
Phascolarctobacterium
A Gram-negative, obligate anaerobic genus within the Firmicutes phylum (family Acidaminococcaceae, class Negativicutes). The primary species P. faecium and the recently characterized P. succinatutens are specialized propionate producers that utilize succinate as their m…
Interventions0 sources
Probiotics for Hashimoto's Thyroiditis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases4 sources
Psoriasis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases7 sources
Rheumatoid Arthritis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Clinical cautions3 sources
STOP: Iodine Supplementation for Graves' Disease
Warning: Clinical Disclaimer: This STOP page represents a hypothesis based on mechanistic evidence and should NOT replace clinical judgment. Always consult with a qualified healthcare provider before modifying any treatment plan. Evidence quality ratings reflect the str…
Clinical cautions4 sources
STOP: Iodine Supplementation for Hashimoto's Thyroiditis
Warning: Clinical Disclaimer: This STOP page represents a hypothesis based on mechanistic evidence and should NOT replace clinical judgment. Always consult with a qualified healthcare provider before modifying any treatment plan.
Clinical cautions3 sources
STOP: Iron Supplementation for Graves' Disease
Warning: Clinical Disclaimer: This STOP page represents a hypothesis based on mechanistic evidence and should NOT replace clinical judgment. Always consult with a qualified healthcare provider before modifying any treatment plan. Evidence quality ratings reflect the str…
Mechanisms3 sources
Thyroid Autoimmunity
Autoimmune thyroid diseases (AITDs) -- hashimotos thyroiditis and graves disease -- are the most common organ-specific autoimmune conditions, affecting 5-10% of the global population. The thyroid gland sits at a remarkable intersection of metal biology and immune regula…
Mechanisms9 sources
Tryptophan Metabolism
Tryptophan (Trp) is an essential amino acid metabolized via three competing pathways: the kynurenine pathway, the serotonin pathway, and the microbial indole pathway. The balance among these pathways is profoundly influenced by the gut microbiome, inflammation, and meta…
Diseases10 sources
Type 1 Diabetes
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases6 sources
Ulcerative Colitis
A chronic inflammatory bowel disease characterized by continuous mucosal inflammation of the colon, extending proximally from the rectum. Unlike crohns disease, UC is limited to the colon, affects only the mucosa/submucosa (not transmural), produces no skip lesions, and…
Interventions0 sources
Vitamin D Supplementation
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
Metals62 sources
Zinc
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms8 sources
Zonulin
A protein (pre-haptoglobin-2) that reversibly modulates tight junction permeability in the intestinal epithelium. Identified by Alessio Fasano in 2000, zonulin is the only known physiological regulator of intestinal paracellular permeability and has become the most wide…