Lachnobacterium

Lachnobacterium is a genus of Gram-positive, obligate anaerobic bacteria within the family Lachnospiraceae (phylum Firmicutes). It is a commensal member of the healthy human gut microbiota, though relatively understudied compared to other Lachnospiraceae genera.

Lachnobacterium has been identified as depleted in gynecological conditions involving gut microbiome disruption. Reduced abundance has been reported in endometriosis ([1], cross-sectional) and premature ovarian insufficiency ([2], cross-sectional), consistent with broader Lachnospiraceae loss observed in estrogen-related disorders.

Cross-References

References (10)

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  2. Wu J, Zhuo Y, Liu Y et al. (2021). Association between premature ovarian insufficiency and gut microbiota. BMC Pregnancy and Childbirth. doi:10.1186/s12884-021-03855-w
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  7. Lucia N. Peralta-Marzal, David Rojas-Velazquez, Douwe Rigters et al. (2024). Peralta-Marzal 2024 — A Robust Microbiome Signature for Autism Spectrum Disorder Across Different Studies Using Machine Learning. Scientific Reports. doi:10.1038/s41598-023-50601-7
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