Lachnobacterium is a genus of Gram-positive, obligate anaerobic bacteria within the family Lachnospiraceae (phylum Firmicutes). It is a commensal member of the healthy human gut microbiota, though relatively understudied compared to other Lachnospiraceae genera.
Lachnobacterium has been identified as depleted in gynecological conditions involving gut microbiome disruption. Reduced abundance has been reported in endometriosis (svensson 2021 associations endometriosis gut microbiota, cross-sectional) and premature ovarian insufficiency (wu 2021 premature ovarian insufficiency gut microbiota, cross-sectional), consistent with broader Lachnospiraceae loss observed in estrogen-related disorders.
Cross-References
- lachnospiraceae — parent family
- endometriosis — condition of depletion
- butyrivibrio — related Lachnospiraceae genus with similar depletion patterns