Mechanisms4 sources
Estrobolome
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Search: “estrobolome”
Ranked matches across titles, topics, categories, and article introductions.
32 records in this view
Microorganisms10 sources
Actinobacteria (Actinomycetota)
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Mechanisms5 sources
Aromatase
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Mechanisms11 sources
Bacterial Contamination Hypothesis
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Mechanisms3 sources
Bacterial Vaginosis
Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age, affecting an estimated 29% of women globally. Rather than an infection by a single pathogen, BV represents a polymicrobial dysbiotic state -- a collapse of the protective Lactoba…
Mechanisms7 sources
Beta-Glucuronidase
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Diseases19 sources
Breast Cancer
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Microorganisms8 sources
Eggerthella lenta
A Gram-positive obligate anaerobe and key estrobolome member that links metabolic dysbiosis to hormone-driven diseases, particularly endometriosis. E. lenta is remarkable for its ability to inactivate cardiac glycosides (like digoxin) and to produce beta-glucuronidase, …
Mechanisms8 sources
Endocrine Disruptors
Exogenous chemicals that interfere with hormone synthesis, secretion, transport, binding, or elimination, mimicking or blocking endogenous hormones at physiologically relevant concentrations. In the metallomics-microbiome framework, endocrine disruptors occupy a critica…
Diseases11 sources
Endometriosis
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Mechanisms8 sources
Enterohepatic Circulation
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Microorganisms8 sources
Escherichia
Escherichia is a genus of Gram-negative, facultatively anaerobic bacteria in the Enterobacteriaceae family. The primary species E. coli is simultaneously the most studied bacterium in biology and one of the most consistently enriched organisms in disease-associated micr…
Mechanisms3 sources
Estrogen Recirculation
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Diseases13 sources
Female Infertility
Affects approximately 48 million women worldwide (WHO global infertility prevalence estimates). From a microbiome-metallomics perspective, female infertility sits at the intersection of the estrobolome (microbial estrogen metabolism), heavy metal reproductive toxicity (…
Reference0 sources
Glossary
Alphabetical definitions of specialist terms used throughout this wiki. Where a full concept page exists, the term links to it. --- AhR (aryl hydrocarbon receptor) -- A ligand-activated transcription factor that senses microbial metabolites (especially indoles from tryp…
Mechanisms8 sources
Gut-Gonadal Axis
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Mechanisms5 sources
Gut-Vagina Axis
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Other0 sources
Hungatella
--- title: Hungatella type: entity subtype: microbe created: 2026-04-10 updated: 2026-04-16 lastsubstantiveupdate: 2026-04-16 sources: [altinok-dindar-2023-gut-microbiota-breast-cancer-diet, qin-2024-consistent-microbiome-signatures-old-young-onset-crc, zhang-2025-gut-v…
Microorganisms6 sources
Lactobacillus crispatus
A Gram-positive, facultatively anaerobic bacterium that is the dominant species in the healthy human vaginal microbiome and a defining member of Community State Type I (CST-I). L. crispatus dominance is associated with reproductive health, pathogen resistance, and reduc…
Diseases17 sources
Long COVID
Post-acute sequelae of SARS-CoV-2 infection (PASC), affecting an estimated 10-30% of COVID-19 survivors (WHO and CDC post-acute surveillance estimates) with symptoms persisting 12 weeks. Characterized by fatigue, cognitive dysfunction ("brain fog"), exercise intolerance…
Mechanisms3 sources
Metalloestrogen
A metal ion that activates estrogen receptors and mimics the biological effects of estradiol. Metalloestrogens represent a distinct class of endocrine-disrupting compounds where the active agent is an inorganic metal rather than an organic xenoestrogen like BPA or phtha…
Diseases6 sources
Ovarian Cancer
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Diseases13 sources
Postpartum Depression
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Diseases4 sources
Premature Ovarian Insufficiency
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases6 sources
Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) affects 3-8% of menstruating individuals Epperson et al. 2012, causing severe mood disturbances, irritability, anxiety, and physical symptoms during the luteal phase of the menstrual cycle. Distinguished from premenstrual syndrome …
Mechanisms4 sources
Premenstrual Syndrome
Premenstrual syndrome (PMS) affects an estimated 20-40% of women of reproductive age, characterized by cyclical physical and psychological symptoms in the luteal phase (post-ovulation, pre-menstruation). While PMS has traditionally been attributed solely to hormonal flu…
Interventions0 sources
Probiotics (Lactobacillus + Bifidobacterium) for PCOS
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
Interventions0 sources
Probiotics for Postpartum Depression
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Mechanisms5 sources
Serotonin-Estrogen Axis
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Clinical cautions6 sources
STOP: Standard (Unselected) Probiotics for Endometriosis
Research summary -- not medical advice. This page synthesizes published research on why a commonly recommended intervention may be counterproductive in this specific clinical context. Consult a qualified healthcare provider before making any changes to treatment.
Microorganisms6 sources
Streptococcus agalactiae
Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is a Gram-positive, facultatively anaerobic coccus that exists in two clinical contexts: (1) as a major neonatal pathogen causing life-threatening meningitis and sepsis in newborns, and (2) as an enric…
Analyses0 sources
The zinc supplementation question — Breast Cancer
Zinc deficiency is a consistent finding in breast cancer, and Zn plays key roles in immunity (T cell differentiation), p53 activation, and SOD cofactor function. Yet supplementation data are limited, and in the Sister Study, zinc showed a dose-related positive associati…