Mechanisms8 sources
GABA (Gamma-Aminobutyric Acid)
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Search: “GABA”
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Mechanisms5 sources
Allopregnanolone
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Diseases8 sources
Anxiety Disorders
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Microorganisms6 sources
Lactobacillus reuteri
Lactobacillus reuteri is one of the most extensively studied probiotic species, notable for its production of neuroactive metabolites (GABA, histamine) and its effects on the hypothalamic-pituitary-gonadal axis (testosterone, oxytocin).
Diseases7 sources
Major Depressive Disorder
Major depressive disorder (MDD) is a psychiatric condition characterized by persistent depressed mood, anhedonia, and cognitive/somatic symptoms. In the WikiBiome framework, MDD is a paradigm case for the gut brain axis: gut dysbiosis drives systemic inflammation and ne…
Diseases6 sources
Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) affects 3-8% of menstruating individuals Epperson et al. 2012, causing severe mood disturbances, irritability, anxiety, and physical symptoms during the luteal phase of the menstrual cycle. Distinguished from premenstrual syndrome …