Diseases6 sources
Cystic Fibrosis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Search: “ROS”
Ranked matches across titles, topics, categories, and article introductions, filtered to disease.
43 records in this view
Diseases5 sources
Multiple Sclerosis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases8 sources
Anxiety Disorders
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases7 sources
Barrett's Esophagus
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases8 sources
Bipolar Disorder
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases14 sources
Cardiovascular Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases8 sources
Celiac Disease
Celiac disease is a chronic autoimmune condition triggered by dietary gluten (gliadin proteins from wheat, barley, and rye) in genetically susceptible individuals (HLA-DQ2/DQ8, carried by ~30-40% of Europeans but penetrant in only ~1% of carriers). Gluten exposure cause…
Diseases8 sources
Cerebral Palsy
Cerebral palsy (CP) is the most common motor disability in childhood, affecting 2-3 per 1,000 live births allen 2021 multi organ dysfunction cerebral palsy. Characterized by non-progressive disturbances in movement and posture arising from injury to the developing brain…
Diseases8 sources
Cholestasis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases3 sources
Chronic Fatigue Syndrome
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases4 sources
Cirrhosis
Cirrhosis is end-stage liver fibrosis characterized by nodular regeneration, portal hypertension, and progressive hepatic failure. The gut-liver axis is central: portal venous blood delivers gut-derived LPS, bacterial DNA, and viable bacteria directly to the liver, and …
Diseases8 sources
Coronary Artery Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases8 sources
Dermatitis Herpetiformis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases3 sources
Diabetic Kidney Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases5 sources
Epilepsy
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases8 sources
Erectile Dysfunction
Erectile dysfunction (ED) affects 30-50% of men aged 40-70 Feldman et al. 1994, with prevalence increasing with age. Conventionally understood as a vascular and/or neurogenic disorder, ED is now recognized as a condition with a significant gut microbiome component -- th…
Diseases13 sources
Female Infertility
Affects approximately 48 million women worldwide (WHO global infertility prevalence estimates). From a microbiome-metallomics perspective, female infertility sits at the intersection of the estrobolome (microbial estrogen metabolism), heavy metal reproductive toxicity (…
Diseases8 sources
Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome affecting 2-4% of the global population Heidari et al. 2017, characterized by widespread musculoskeletal pain, fatigue, cognitive dysfunction ("fibro fog"), and sleep disturbances. Conventionally attributed to central sensiti…
Diseases5 sources
Gastric Adenocarcinoma
The most common malignancy of the stomach, accounting for over 95% of gastric cancers. helicobacter pylori infection is the strongest known risk factor, classified as a Group 1 carcinogen by IARC. In the metallomics framework, gastric adenocarcinoma reveals a striking d…
Diseases6 sources
Gastric Cancer
The fifth most common cancer worldwide and third leading cause of cancer death, with over 1 million new cases annually. Gastric cancer stands unique in this wiki as the disease where a single microorganism -- helicobacter pylori -- provides the dominant causal pathway, …
Diseases6 sources
Gastric Ulcer
A breach in the gastric mucosal lining extending through the muscularis mucosae, most commonly caused by helicobacter pylori infection or chronic NSAID use. Gastric ulceration represents a critical node in the upper GI disease continuum, linking gerd, chronic gastritis,…
Diseases8 sources
Gestational Diabetes Mellitus
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Diseases4 sources
Hepatitis
Hepatitis (liver inflammation) encompasses viral (HBV, HCV, HAV), autoimmune, alcoholic, and toxin-induced forms. In the WikiBiome framework, the gut-liver axis is central — portal blood delivers gut-derived microbial products (LPS, bacterial DNA) directly to the liver …
Diseases2 sources
Hidradenitis Suppurativa
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases5 sources
HIV/AIDS
HIV (Human Immunodeficiency Virus) causes progressive CD4+ T cell depletion leading to AIDS. In the WikiBiome framework, HIV is notable for the gut-centric model of disease progression: HIV preferentially destroys gut-associated lymphoid tissue (GALT) early in infection…
Diseases4 sources
Huntington's Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases11 sources
Inflammatory Bowel Disease (IBD)
An umbrella term for chronic relapsing-remitting inflammatory conditions of the gastrointestinal tract, principally crohns disease (CD; transmural, any GI segment) and ulcerative colitis (UC; mucosal, colon only). Approximately 6 million patients worldwide. IBD represen…
Diseases7 sources
Major Depressive Disorder
Major depressive disorder (MDD) is a psychiatric condition characterized by persistent depressed mood, anhedonia, and cognitive/somatic symptoms. In the WikiBiome framework, MDD is a paradigm case for the gut brain axis: gut dysbiosis drives systemic inflammation and ne…
Diseases5 sources
Migraine
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases18 sources
Necrotizing Enterocolitis
Necrotizing enterocolitis (NEC) is the most common and lethal gastrointestinal emergency in premature infants, affecting 5-12% of very low birth weight neonates (<1500 g) with mortality rates of 20-30%. Characterized by intestinal inflammation, necrosis, and perforation…
Diseases8 sources
Non-Alcoholic Fatty Liver Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases6 sources
Ovarian Cancer
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases22 sources
Pancreatic Cancer
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases5 sources
Pancreatitis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases14 sources
Parkinson's Disease
The second most common neurodegenerative disease, affecting over 10 million people worldwide dorsey 2018 parkinsons incidence meta analysis. Characterized by progressive loss of dopaminergic neurons in the substantia nigra, alpha-synuclein aggregation (Lewy bodies), and…
Diseases5 sources
Pelvic Inflammatory Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases7 sources
Periodontitis
Periodontitis is a chronic inflammatory disease of the periodontal tissues (gingiva, periodontal ligament, alveolar bone) driven by a dysbiotic polymicrobial biofilm in the subgingival pocket. The keystone pathogen is porphyromonas gingivalis, whose zinc-dependent gingi…
Diseases5 sources
Pneumonia
Pneumonia is infection of the lung parenchyma, most commonly caused by streptococcus pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, and viruses (influenza, SARS-CoV-2). In the WikiBiome framework, pneumonia exemplifies the metal battleground at the host-path…
Diseases4 sources
Premature Ovarian Insufficiency
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases6 sources
Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) affects 3-8% of menstruating individuals Epperson et al. 2012, causing severe mood disturbances, irritability, anxiety, and physical symptoms during the luteal phase of the menstrual cycle. Distinguished from premenstrual syndrome …
Diseases4 sources
Psoriasis
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases3 sources
Sepsis
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. In the WikiBiome framework, sepsis represents the catastrophic failure of both colonization resistance (pathogen invasion) and nutritional immunity (metal restriction). Inf…
Diseases3 sources
Tuberculosis
Tuberculosis is caused by mycobacterium tuberculosis, an intracellular pathogen that survives inside macrophage phagosomes. In the WikiBiome framework, TB exemplifies the intracellular metal battleground: M. tuberculosis deploys mycobactins (lipophilic siderophores) and…