Mechanisms9 sources
Endotoxemia
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Search: “endotoxemia”
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12 records in this view
Microorganisms3 sources
Allisonella
A Gram-negative obligate anaerobe identified as a histamine-producing bacterium enriched in dysbiotic microbiota associated with obesity, metabolic syndrome, and metabolic endotoxemia. Allisonella is a minor but functionally significant genus whose primary clinical rele…
Diseases14 sources
Cardiovascular Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases18 sources
Chronic Kidney Disease
A progressive loss of kidney function affecting approximately 850 million people worldwide (10–14% of adults), causing 1.2 million deaths annually. CKD is unique among diseases in this wiki because it occupies both sides of the metal-disease equation: heavy metals (Cd, …
Diseases4 sources
Cirrhosis
Cirrhosis is end-stage liver fibrosis characterized by nodular regeneration, portal hypertension, and progressive hepatic failure. The gut-liver axis is central: portal venous blood delivers gut-derived LPS, bacterial DNA, and viable bacteria directly to the liver, and …
Mechanisms4 sources
Leptin
Leptin is an adipokine (hormone produced by adipose tissue) that signals satiety to the hypothalamus — suppressing appetite and increasing energy expenditure. Leptin resistance (elevated leptin with impaired signaling) is a hallmark of obesity, paralleling insulin resis…
Mechanisms6 sources
Lipopolysaccharide
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Diseases17 sources
Long COVID
Post-acute sequelae of SARS-CoV-2 infection (PASC), affecting an estimated 10-30% of COVID-19 survivors (WHO and CDC post-acute surveillance estimates) with symptoms persisting 12 weeks. Characterized by fatigue, cognitive dysfunction ("brain fog"), exercise intolerance…
Diseases7 sources
Major Depressive Disorder
Major depressive disorder (MDD) is a psychiatric condition characterized by persistent depressed mood, anhedonia, and cognitive/somatic symptoms. In the WikiBiome framework, MDD is a paradigm case for the gut brain axis: gut dysbiosis drives systemic inflammation and ne…
Diseases8 sources
Non-Alcoholic Fatty Liver Disease
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms7 sources
Systemic Inflammation
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Mechanisms6 sources
Tight Junctions
This knowledge-base record is being expanded from WikiBiome’s evidence graph.