Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 16%
- weighted overlap
- 15
- shared signals
Comparison
SchizophreniaandObesity
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 46
- Schizophrenia references
- 31
- Obesity references
- 0
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
2 sharedShared
Only in Schizophrenia
Only in Obesity
Taxa depleted
4 sharedHost response elevated
2 sharedShared
Only in Schizophrenia
CRPSCD14IL 6IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasminZonulinAlpha 1 Antitrypsin
Only in Obesity
Host response depleted
1 sharedShared
Only in Schizophrenia
Only in Obesity
Ecological state
0 sharedShared
None indexed
Only in Schizophrenia
SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis
Only in Obesity
HypoxiaMetal Driven DysbiosisReduced SCFA ProductionIncreased LPSEndotoxemiaIntestinal Permeability IncreaseFermentative MetabolismAcidic MicroenvironmentMetabolic EndotoxemiaReduced Microbial DiversityIncreased Energy HarvestBile Acid DysregulationVirome Depletion
Virulence and functional enzymes
2 sharedShared
LPS BiosynthesisBeta-Glucuronidase
Only in Schizophrenia
Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsSiderophore SystemsIndoleamine 2 3 DioxygenaseTryptophanase