WikiBiomeThe human microbiome encyclopedia
Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

6%
weighted overlap
7
shared signals
Comparison

Necrotizing EnterocolitisandSchizophrenia

2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

19
Necrotizing Enterocolitis references
46
Schizophrenia references
2
shared references
01

Metals elevated or accumulated

1 shared

Shared

Iron

Only in Necrotizing Enterocolitis

None indexed

Only in Schizophrenia

CopperLeadCadmiumArsenic
02

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Necrotizing Enterocolitis

None indexed

Only in Schizophrenia

Glutathione (GSH)
03

Taxa enriched

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

KlebsiellaEscherichia coliClostridium perfringensStaphylococcusKlebsiella pneumoniaeClostridium Perfringens (Toxigenic)Sphingomonas Spp.Clostridium Spp. (Obligate Anaerobe Cluster)Bacteroides/Prevotella (Obligate Anaerobe Cluster)Staphylococcus epidermidisEnterococcus

Only in Schizophrenia

LactobacillusPrevotellaEnterobacteriaceaeStreptococcusVeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocilliumClostridiaBetaproteobacteriaPrevotellaceae
06

Host response depleted

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

ZincDefensinsAcetateLactateSecretory IgA

Only in Schizophrenia

Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins
07

Ecological state

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

Proteobacteria Bloom 2 Weeks Pre DiagnosisVirome Convergence 10 Days Pre OnsetTLR4 Upregulation In Premature EpitheliumBifidobacterium Absence As PreconditionHMO Mediated Colonization ResistanceFeed Forward Barrier DestructionProteobacteria BloomTLR4 Feed Forward LoopVirome ConvergenceImmature BarrierParenteral Iron OverloadBiofilmBile Acid Accumulation ASBT UpregulationMuc2 Depletion Mucosal Barrier FailureObligate Anaerobe Mucosal InvasionGut Brain Axis NDI RiskAntibiotic Driven Richness Nadir Week4

Only in Schizophrenia

SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis
08

Virulence and functional enzymes

1 shared

Shared

LPS Biosynthesis

Only in Necrotizing Enterocolitis

SiderophoresAlpha ToxinPerfringolysin OBiofilm Formation Enzymes

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsSiderophore SystemsBeta-GlucuronidaseIndoleamine 2 3 DioxygenaseTryptophanase