Type-strain-anchored Staphylococcus epidermidis reconstruction with thirteen cocci. Representative, non-diagnostic, not visually separable from other staphylococci, and not a micrograph.
Scientific media record1 verified identifier
- Subject
- Staphylococcus epidermidistaxon · species
- Identifiers
- NCBITaxon:1282
- Review
- Editorial review completeIdentifiers authority-verified · Accessibility validated · · staphylococcus-epidermidis|staphylococcus-epidermidis-morphology-v1.webp
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- Trained-algorithmic mediaCreated with a trained generative algorithm and reviewed by WikiBiome for subject identity, scientific framing, identifiers, provenance, and accessibility.
- Scientific basis
- Staphylococcus epidermidis — NCBI TaxonomyStaphylococcus epidermidis — LPSNStaphylococcus epidermidis morphology
- License
- CC BY-SA 4.0Created
Staphylococcus epidermidis is a Gram-positive, facultative anaerobic coagulase-negative staphylococcus and one of the most abundant commensals of human skin and mucosal surfaces. While generally benign, it is a leading cause of nosocomial infections associated with indwelling medical devices due to its prolific biofilm-forming capacity.
Evidence map2 cited passagesInspect provenance +
S. epidermidis biofilms exhibit notable metal resistance properties. Metal-based antimicrobial strategies targeting biofilm-embedded staphylococci—including methicillin-resistant strains (MRSE)—leverage the organism's metal dependencies as vulnerabilities (). Essential oils and carvacrol-based codrugs have shown antibiofilm activity against S. epidermidi
Beyond skin, S. epidermidis is a component of the genital and intestinal microbiota. It has been identified in the reproductive tract microbiome of women with adenomyosis and associated infertility (), suggesting a role in reproductive tract dysbiosis.
Metal Dependencies and Biofilm#
S. epidermidis biofilms exhibit notable metal resistance properties. Metal-based antimicrobial strategies targeting biofilm-embedded staphylococci—including methicillin-resistant strains (MRSE)—leverage the organism's metal dependencies as vulnerabilities ([1]Sanchez-Rosario 2026 — N-benzyl-N-methyldithiocarbamate (BMDC) Combines with Metals to Produce Antimicrobial and Anti-Biofilm Activity Against MRSA and S. epidermidisYamil Sanchez-Rosario, Natasha R Cornejo, Isaiah S Gonzalez et al. · 2026Open reference 1 ↓).
Essential oils and carvacrol-based codrugs have shown antibiofilm activity against S. epidermidis, disrupting the polysaccharide matrix that shields sessile cells ([2]Cacciatore 2015 — Carvacrol codrugs: a new approach in the antimicrobial planIvana Cacciatore, Mara Di Giulio, Erika Fornasari et al. · 2015Open reference 2 ↓).
Reproductive Tract Associations#
Beyond skin, S. epidermidis is a component of the genital and intestinal microbiota. It has been identified in the reproductive tract microbiome of women with adenomyosis and associated infertility ([3]Ponomaryova 2022 — Changes in microbiota of genital tract and intestines in patients with adenomyosis and infertilityPonomaryova IG, Lisyana TO, Trokhimovych OV et al. · 2022Open reference 3 ↓), suggesting a role in reproductive tract Dysbiosis.
Cross-References#
- Biofilm—S. epidermidis as a model biofilm-forming organism
- Staphylococcus—genus-level page
- adenomyosis—reproductive tract associations
- Antimicrobial Metals—metal-based strategies against staphylococcal biofilms
References 3
Numbered by first appearance in the article, then reconciled with its declared source list.
- 1
Yamil Sanchez-Rosario, Natasha R Cornejo, Isaiah S Gonzalez et al. (2026). Sanchez-Rosario 2026 — N-benzyl-N-methyldithiocarbamate (BMDC) Combines with Metals to Produce Antimicrobial and Anti-Biofilm Activity Against MRSA and S. epidermidis. mSphere.
- 2
Ivana Cacciatore, Mara Di Giulio, Erika Fornasari et al. (2015). Cacciatore 2015 — Carvacrol codrugs: a new approach in the antimicrobial plan. PLOS ONE.
- 3
Ponomaryova IG, Lisyana TO, Trokhimovych OV et al. (2022). Ponomaryova 2022 — Changes in microbiota of genital tract and intestines in patients with adenomyosis and infertility. Medical Research Journal.
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Created “Staphylococcus epidermidis”: Staphylococcus epidermidis is a Gram-positive, facultative anaerobic coagulase-negative staphylococcus and one of the most abundant commensals of human skin and mucosal surfaces. While generally…
Created “Staphylococcus epidermidis”: Staphylococcus epidermidis is a Gram-positive, facultative anaerobic coagulase-negative staphylococcus and one of the most abundant commensals of human skin and mucosal surfaces. While generally… Published sections: Overview; Metal Dependencies and Biofilm; Reproductive Tract Associations; Cross-References. · WikiBiome Deploy Bot · +43 −0
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