Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 18%
- weighted overlap
- 18
- shared signals
Comparison
Graves' DiseaseandChronic Kidney Disease
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 22
- Graves' Disease references
- 34
- Chronic Kidney Disease references
- 0
- shared references
Metals depleted or redistributed
1 sharedShared
Only in Graves' Disease
Only in Chronic Kidney Disease
Taxa enriched
4 sharedShared
Only in Graves' Disease
Only in Chronic Kidney Disease
Eggerthella lentaDesulfovibrionalesFlavonifractorClostridiaceaeMethanobacteriaParabacteroidesClostridiumRuminococcusPseudomonas aeruginosa
Taxa depleted
6 sharedShared
Only in Graves' Disease
Only in Chronic Kidney Disease
Host response elevated
2 sharedShared
Only in Graves' Disease
Only in Chronic Kidney Disease
CRPIL 6IL 18TNF-alpha (Tumor Necrosis Factor Alpha)TLR2 TLR4NF KappaBNLRP3 InflammasomeSCD14Free Light Chains KappaFree Light Chains LambdaIndoxyl SulfateP Cresyl SulfateTrimethylamine N-Oxide (TMAO)MalondialdehydeUric AcidFerritin
Host response depleted
0 sharedShared
None indexed
Only in Graves' Disease
SelenoproteinsGlutathione PeroxidaseThioredoxin ReductaseDeiodinases
Only in Chronic Kidney Disease
Alpha-KlothoButyratePropionateAcetateIndole Propionic AcidTaurineBCAAsVitamin DTotal Antioxidant CapacityENOSGlutathione (GSH)GPX4
Ecological state
0 sharedShared
None indexed
Only in Graves' Disease
Intestinal PermeabilityTh17 Treg ImbalanceMolecular MimicryEstrogen RecirculationSCFA DeficiencyLPS TranslocationBidirectional Gut Thyroid Axis
Only in Chronic Kidney Disease
Saccharolytic To Proteolytic ShiftSCFA DepletionGut Barrier DysfunctionUremic Toxin AccumulationAmmonia PH DisruptionMetal Microbiome Co ResistanceAntibiotic Resistance Gene EnrichmentVicious Cycle BidirectionalConstipation As Progression MarkerVicious Cycle Metal AccumulationStage 3b Ecological TransitionUremic Toxin ProductionMetal Antibiotic Co ResistanceFerroptosisGut Barrier DisruptionDialysis Irreversibility
Virulence and functional enzymes
2 sharedShared
Only in Graves' Disease
LPSThyroid Peroxidase Mimicry AntigensLPS Endotoxin
Only in Chronic Kidney Disease
UreaseTryptophanaseTyrosine DecarboxylaseTMA LyaseAromatic Amino Acid Degradation EnzymesHydrogen Sulfide SynthaseCadA Cadmium ATPaseArsC Arsenate ReductaseP Cresyl Sulfate SynthaseIndoxyl Sulfate Synthase