Heavy-atom connectivity orientation for taurine (2-aminoethanesulfonic acid). Hydrogens, formal charge, protonation state, and measured conformation are intentionally not shown; this is an educational reconstruction, not an experimental structure.
Scientific media record3 verified identifiers
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- Taurinebiological-process
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- WikiBiome:taurinePubChem:1123ChEBI:15891
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- Editorial review completeIdentifiers authority-verified · Accessibility validated · · taurine|taurine-mechanism-v1.webp
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- Trained-algorithmic mediaCreated with a trained generative algorithm and reviewed by WikiBiome for subject identity, scientific framing, identifiers, provenance, and accessibility.
- Scientific basis
- Taurine — PubChemTaurine — ChEBIVersatile Triad Alliance: Bile Acid, Taurine and MicrobiotaTaurine
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- CC BY-SA 4.0Created
Taurine (2-aminoethanesulfonic acid) is a sulfur-containing amino acid abundant in bile, heart, brain, and retina. Its primary metabolic role is bile acid conjugation—taurocholate and taurochenodeoxycholate are the taurine-conjugated primary bile acids that BSH-producing gut bacteria deconjugate, releasing free taurine into the colonic lumen.
Taurine also functions as an antioxidant, osmoregulator, membrane stabilizer, and weak metal chelator.
Evidence map2 cited passagesInspect provenance +
BSH deconjugation releases taurine → colonic taurine is metabolized by sulfate-reducing bacteria (desulfovibrio) to produce hydrogen sulfide. High-taurine diets (meat-rich) thus indirectly increase H₂S production.
Taurine supplementation shows cardiovascular protective effects via anti-inflammatory and antioxidant mechanisms.
Microbiome Interface#
BSH deconjugation releases taurine → colonic taurine is metabolized by sulfate-reducing bacteria (Desulfovibrio) to produce Hydrogen Sulfide (H₂S). High-taurine diets (meat-rich) thus indirectly increase H₂S production.[1]Rezen et al. 2022 — The Role of Bile Acids in CarcinogenesisRezen T, Rozman D, Kovacs T et al. · 2022Open reference 1 ↓
Taurine supplementation shows cardiovascular protective effects via anti-inflammatory and antioxidant mechanisms.[2]Fermented Food: Should Patients with Cardiometabolic Diseases Go Back to an Early Neolithic Diet?Denise Mafra, Natalia A. Borges, Livia Alvarenga et al. · 2022Open reference 2 ↓[3]Microbiota-derived short-chain fatty acids: Implications for cardiovascular and metabolic diseaseYingdong Lu, Yang Zhang, Xin Zhao et al. · 2022Open reference 3 ↓
Cross-References#
- Bile Salt Hydrolase (BSH)—releases taurine from conjugated bile acids
- Bile Acid Metabolism—taurine conjugation context
- Hydrogen Sulfide (H₂S)—taurine as sulfur source for H₂S production
- Desulfovibrio—taurine-metabolizing sulfate reducer
References 3
Numbered by first appearance in the article, then reconciled with its declared source list.
- 1
Rezen T, Rozman D, Kovacs T et al. (2022). Rezen et al. 2022 — The Role of Bile Acids in Carcinogenesis. Cellular and Molecular Life Sciences.
- 2
Denise Mafra, Natalia A. Borges, Livia Alvarenga et al. (2022). Fermented Food: Should Patients with Cardiometabolic Diseases Go Back to an Early Neolithic Diet?. Critical Reviews in Food Science and Nutrition.
- 3
Yingdong Lu, Yang Zhang, Xin Zhao et al. (2022). Microbiota-derived short-chain fatty acids: Implications for cardiovascular and metabolic disease. Frontiers in Cardiovascular Medicine.
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Created “Taurine”: Taurine (2-aminoethanesulfonic acid) is a sulfur-containing amino acid abundant in bile, heart, brain, and retina. Its primary metabolic role is bile acid conjugation — taurocholate and…
Created “Taurine”: Taurine (2-aminoethanesulfonic acid) is a sulfur-containing amino acid abundant in bile, heart, brain, and retina. Its primary metabolic role is bile acid conjugation — taurocholate and… Published sections: Taurine; Microbiome Interface; Cross-References. · WikiBiome Deploy Bot · +32 −0
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