Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Postpartum DepressionandColorectal Cancer

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

56: Postpartum Depression references
36: Colorectal Cancer references
0: shared references

Metals elevated or accumulated

3 shared

Shared

Copper Cadmium Lead

Only in Postpartum Depression

None indexed

Only in Colorectal Cancer

Iron Zinc Nickel Arsenic Chromium

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Postpartum Depression

EnterobacteriaceaeAlphaproteobacteriaBilophila Desulfovibrio Dialister Enterococcus

Only in Colorectal Cancer

Fusobacterium nucleatum Fusobacterium varium Bacteroides fragilis Parvimonas micra Peptostreptococcus stomatis Clostridium symbiosum Porphyromonas gingivalis Akkermansia muciniphila Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Taxa depleted

3 shared

Shared

Bifidobacterium Faecalibacterium prausnitzii Lachnospiraceae

Only in Postpartum Depression

Phascolarctobacterium Veillonella Coprococcus Eubacterium Clostridium Butyricicoccus Holdemanella

Only in Colorectal Cancer

Roseburia Prevotella copri Ruminococcus albus Dialister Lactobacillus Ruminococcus

Host response elevated

3 shared

Shared

HepcidinIL 6TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Postpartum Depression

CRPIDOCeruloplasmin Copper

Only in Colorectal Cancer

IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Calprotectin (S100A8/A9)Lipocalin-2

Host response depleted

0 shared

Shared

None indexed

Only in Postpartum Depression

Zinc Tryptophan GABA (Gamma-Aminobutyric Acid)SCFAFerritin Selenium

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione PeroxidaseGlutathione (GSH)

Ecological state

1 shared

Shared

SCFA Depletion

Only in Postpartum Depression

Postpartum Hormonal CrashEstrogen Progesterone WithdrawalIDO Kynurenine ActivationTryptophan DiversionHPA Axis DysregulationGut Brain Axis DisruptionBile Acid DysmetabolismPrenatal Microbiome SeedingIntergenerational Dysbiosis TransmissionBarrier DysfunctionHormonal DysregulationTryptophan Kynurenine ShuntingIntergenerational Microbiome Transmission

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Virulence and functional enzymes

2 shared

Shared

Beta-Glucuronidase Siderophores

Only in Postpartum Depression

LPS EndotoxinIDO Indoleamine 2 3 DioxygenaseBile Salt Hydrolase (BSH)Sulfite ReductaseSiderophores EnterobactinLPS Biosynthesis Enzymes

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksUrease Glyoxalase IBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase