Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 20%
- weighted overlap
- 17
- shared signals
Comparison
Graves' DiseaseandSchizophrenia
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 22
- Graves' Disease references
- 46
- Schizophrenia references
- 0
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
5 sharedShared
Only in Graves' Disease
Only in Schizophrenia
Taxa depleted
4 sharedHost response elevated
2 sharedShared
Only in Graves' Disease
Only in Schizophrenia
CRPSCD14IL 6IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasminZonulinAlpha 1 Antitrypsin
Host response depleted
0 sharedShared
None indexed
Only in Graves' Disease
SelenoproteinsGlutathione PeroxidaseThioredoxin ReductaseDeiodinases
Only in Schizophrenia
Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins
Ecological state
1 sharedShared
Th17 Treg Imbalance
Only in Graves' Disease
Intestinal PermeabilityMolecular MimicryEstrogen RecirculationSCFA DeficiencyLPS TranslocationBidirectional Gut Thyroid Axis
Only in Schizophrenia
SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationVirome Dysbiosis
Virulence and functional enzymes
1 sharedShared
Only in Graves' Disease
Only in Schizophrenia
Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsIndoleamine 2 3 DioxygenaseTryptophanase