Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Colorectal CancerandPostpartum Depression

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

36: Colorectal Cancer references
56: Postpartum Depression references
0: shared references

Metals elevated or accumulated

3 shared

Shared

Cadmium Lead Copper

Only in Colorectal Cancer

Iron Zinc Nickel Arsenic Chromium

Only in Postpartum Depression

None indexed

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Colorectal Cancer

Fusobacterium nucleatum Fusobacterium varium Bacteroides fragilis Parvimonas micra Peptostreptococcus stomatis Clostridium symbiosum Porphyromonas gingivalis Akkermansia muciniphila Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Only in Postpartum Depression

EnterobacteriaceaeAlphaproteobacteriaBilophila Desulfovibrio Dialister Enterococcus

Taxa depleted

3 shared

Shared

Lachnospiraceae Faecalibacterium prausnitzii Bifidobacterium

Only in Colorectal Cancer

Roseburia Prevotella copri Ruminococcus albus Dialister Lactobacillus Ruminococcus

Only in Postpartum Depression

Phascolarctobacterium Veillonella Coprococcus Eubacterium Clostridium Butyricicoccus Holdemanella

Host response elevated

3 shared

Shared

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)Hepcidin

Only in Colorectal Cancer

IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Calprotectin (S100A8/A9)Lipocalin-2

Only in Postpartum Depression

CRPIDOCeruloplasmin Copper

Host response depleted

0 shared

Shared

None indexed

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione PeroxidaseGlutathione (GSH)

Only in Postpartum Depression

Zinc Tryptophan GABA (Gamma-Aminobutyric Acid)SCFAFerritin Selenium

Ecological state

1 shared

Shared

SCFA Depletion

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Only in Postpartum Depression

Postpartum Hormonal CrashEstrogen Progesterone WithdrawalIDO Kynurenine ActivationTryptophan DiversionHPA Axis DysregulationGut Brain Axis DisruptionBile Acid DysmetabolismPrenatal Microbiome SeedingIntergenerational Dysbiosis TransmissionBarrier DysfunctionHormonal DysregulationTryptophan Kynurenine ShuntingIntergenerational Microbiome Transmission

Virulence and functional enzymes

2 shared

Shared

Siderophores Beta-Glucuronidase

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksUrease Glyoxalase IBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase

Only in Postpartum Depression

LPS EndotoxinIDO Indoleamine 2 3 DioxygenaseBile Salt Hydrolase (BSH)Sulfite ReductaseSiderophores EnterobactinLPS Biosynthesis Enzymes