Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

10%: weighted overlap
9: shared signals

First condition

Second condition

Comparison

Celiac DiseaseandChronic Kidney Disease

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

8: Celiac Disease references
34: Chronic Kidney Disease references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Nickel

Only in Celiac Disease

None indexed

Only in Chronic Kidney Disease

Cadmium Lead Arsenic Mercury ChromiumIron In Tubular CellsThallium

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Celiac Disease

Bacteroides fragilis Proteobacteria (Pseudomonadota)Staphylococcus aureus

Only in Chronic Kidney Disease

Eggerthella lenta Enterobacteriaceae Desulfovibrionales Flavonifractor CollinsellaClostridiaceaeMethanobacteriaParabacteroides Clostridium Ruminococcus Lactobacillus Pseudomonas aeruginosa

Taxa depleted

4 shared

Shared

Bifidobacterium Faecalibacterium prausnitzii Lachnospiraceae Prevotella

Only in Celiac Disease

Lactobacillus

Only in Chronic Kidney Disease

Roseburia Lachnospira Coprococcus Akkermansia muciniphila Eubacterium rectale Ruminococcus bromii Anaerostipes Blautia

Host response elevated

0 shared

Shared

None indexed

Only in Celiac Disease

Zonulin

Only in Chronic Kidney Disease

CRPIL 6IL 18TNF-alpha (Tumor Necrosis Factor Alpha)TLR2 TLR4NF KappaBNLRP3 InflammasomeSCD14Free Light Chains KappaFree Light Chains LambdaIndoxyl SulfateP Cresyl SulfateTrimethylamine N-Oxide (TMAO)MalondialdehydeUric AcidHepcidin Ferritin Lipocalin-2

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Celiac Disease

None indexed

Only in Chronic Kidney Disease

Alpha-Klotho ButyratePropionateAcetateIndole Propionic AcidTaurineBCAAsVitamin DTotal Antioxidant CapacityENOSGPX4

Ecological state

0 shared

Shared

None indexed

Only in Celiac Disease

Villous AtrophyIncreased Intestinal PermeabilityGluten Mediated Tight Junction DisassemblyNickel Allergic Contact Mucositis

Only in Chronic Kidney Disease

Saccharolytic To Proteolytic ShiftSCFA DepletionGut Barrier DysfunctionUremic Toxin AccumulationAmmonia PH DisruptionMetal Microbiome Co ResistanceAntibiotic Resistance Gene EnrichmentVicious Cycle BidirectionalConstipation As Progression MarkerVicious Cycle Metal AccumulationStage 3b Ecological TransitionUremic Toxin ProductionMetal Antibiotic Co ResistanceFerroptosisGut Barrier DisruptionDialysis Irreversibility

Virulence and functional enzymes

1 shared

Shared

Beta-Glucuronidase

Only in Celiac Disease

Bacterial ProteasesTissue Transglutaminase 2 Mimicry

Only in Chronic Kidney Disease

UreaseTryptophanaseTyrosine DecarboxylaseTMA LyaseSiderophoresAromatic Amino Acid Degradation EnzymesHydrogen Sulfide SynthaseCadA Cadmium ATPaseArsC Arsenate ReductaseP Cresyl Sulfate SynthaseIndoxyl Sulfate Synthase