Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

18%: weighted overlap
17: shared signals

First condition

Second condition

Comparison

SchizophreniaandFibromyalgia

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

46: Schizophrenia references
9: Fibromyalgia references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Schizophrenia

Iron Lead Cadmium Arsenic

Only in Fibromyalgia

None indexed

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Streptococcus

Only in Schizophrenia

Lactobacillus Prevotella Enterobacteriaceae VeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria Prevotellaceae

Only in Fibromyalgia

Eggerthella Flavonifractor Coprococcus Collinsella Eggerthella lentaCoprococcus 2

Taxa depleted

4 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium Lachnospiraceae

Only in Schizophrenia

Coprococcus Blautia Saccharomyces cerevisiae Desulfovibrio Veillonellaceae

Only in Fibromyalgia

Bacteroides vulgatus Bacteroides uniformis

Host response elevated

3 shared

Shared

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)Ceruloplasmin

Only in Schizophrenia

CRPSCD14IL-1beta (Interleukin-1 Beta)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperHepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Only in Fibromyalgia

Pro Inflammatory CytokinesCopperSerum Butyrate

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Schizophrenia

Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Only in Fibromyalgia

GPX3Ferritin Iron SeleniumGlutathione Peroxidase 3Serotonin

Ecological state

3 shared

Shared

SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine Shunting

Only in Schizophrenia

Transkingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Only in Fibromyalgia

Butyrate ParadoxBarrier DysfunctionCopper Iron Axis ImbalanceCentral Sensitization

Virulence and functional enzymes

3 shared

Shared

LPS BiosynthesisIndoleamine 2 3 DioxygenaseTryptophanase

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsSiderophore SystemsBeta-Glucuronidase

Only in Fibromyalgia

Pro Inflammatory Metabolite SynthesisCopper Dependent OxidasesNeurotoxic Metabolite Production