Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

PancreatitisandSchizophrenia

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

6: Pancreatitis references
46: Schizophrenia references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Iron

Only in Pancreatitis

None indexed

Only in Schizophrenia

Copper Lead Cadmium Arsenic

Metals depleted or redistributed

1 shared

Taxa enriched

3 shared

Shared

Candida albicans Veillonella Streptococcus

Only in Pancreatitis

Klebsiella pneumoniae Acinetobacter Pseudomonas aeruginosa Escherichia coli AspergillusCoprococcus3

Only in Schizophrenia

Lactobacillus Prevotella EnterobacteriaceaeSuccinivibrioTrichosporonPurpureocillium Clostridia Betaproteobacteria Prevotellaceae

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium

Only in Pancreatitis

Eubacterium rectalePrevotella9

Only in Schizophrenia

Coprococcus Blautia Saccharomyces cerevisiae Desulfovibrio Veillonellaceae Lachnospiraceae

Host response elevated

2 shared

Shared

IL 6CRP

Only in Pancreatitis

WBCLipaseAmylase

Only in Schizophrenia

SCD14IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin Hepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Host response depleted

0 shared

Shared

None indexed

Only in Pancreatitis

Butyrate AcetateSCFA Synthesis Capacity

Only in Schizophrenia

Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Ecological state

1 shared

Shared

Gut Barrier Dysfunction

Only in Pancreatitis

Bacterial TranslocationFungal DysbiosisPolymicrobial InfectionSCFA Synthesis LossBiofilm

Only in Schizophrenia

SCFA DepletionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Virulence and functional enzymes

1 shared

Shared

LPS Biosynthesis

Only in Pancreatitis

SiderophoresType II Secretion SystemFungal Phospholipases

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsSiderophore SystemsBeta-GlucuronidaseIndoleamine 2 3 DioxygenaseTryptophanase