Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

18%: weighted overlap
17: shared signals

First condition

Second condition

Comparison

FibromyalgiaandSchizophrenia

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Fibromyalgia references
46: Schizophrenia references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Fibromyalgia

None indexed

Only in Schizophrenia

Iron Lead Cadmium Arsenic

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Streptococcus

Only in Fibromyalgia

Eggerthella Flavonifractor Coprococcus Collinsella Eggerthella lentaCoprococcus 2

Only in Schizophrenia

Lactobacillus Prevotella Enterobacteriaceae VeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria Prevotellaceae

Taxa depleted

4 shared

Shared

Faecalibacterium prausnitzii Bifidobacterium Lachnospiraceae Roseburia

Only in Fibromyalgia

Bacteroides vulgatus Bacteroides uniformis

Only in Schizophrenia

Coprococcus Blautia Saccharomyces cerevisiae Desulfovibrio Veillonellaceae

Host response elevated

3 shared

Shared

Ceruloplasmin TNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Only in Fibromyalgia

Pro Inflammatory CytokinesCopperSerum Butyrate

Only in Schizophrenia

CRPSCD14IL-1beta (Interleukin-1 Beta)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperHepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Fibromyalgia

GPX3Ferritin Iron SeleniumGlutathione Peroxidase 3Serotonin

Only in Schizophrenia

Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Ecological state

3 shared

Shared

SCFA DepletionTryptophan Kynurenine ShuntingGut Barrier Dysfunction

Only in Fibromyalgia

Butyrate ParadoxBarrier DysfunctionCopper Iron Axis ImbalanceCentral Sensitization

Only in Schizophrenia

Transkingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Virulence and functional enzymes

3 shared

Shared

TryptophanaseIndoleamine 2 3 DioxygenaseLPS Biosynthesis

Only in Fibromyalgia

Pro Inflammatory Metabolite SynthesisCopper Dependent OxidasesNeurotoxic Metabolite Production

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsSiderophore SystemsBeta-Glucuronidase