Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

13%: weighted overlap
11: shared signals

First condition

Second condition

Comparison

SchizophreniaandInflammatory Bowel Disease (IBD)

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

46: Schizophrenia references
19: Inflammatory Bowel Disease (IBD) references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Schizophrenia

Iron Lead Cadmium Arsenic

Only in Inflammatory Bowel Disease (IBD)

Iron Mucosal

Metals depleted or redistributed

2 shared

Shared

Zinc Glutathione (GSH)

Only in Schizophrenia

None indexed

Only in Inflammatory Bowel Disease (IBD)

Iron SystemicSelenium Manganese

Taxa enriched

1 shared

Taxa depleted

4 shared

Shared

Faecalibacterium prausnitzii Roseburia Blautia Bifidobacterium

Only in Schizophrenia

Coprococcus Saccharomyces cerevisiae Desulfovibrio Veillonellaceae Lachnospiraceae

Only in Inflammatory Bowel Disease (IBD)

Lachnospiraceae (Family)Prevotella

Host response elevated

2 shared

Shared

Hepcidin Lipocalin-2

Only in Schizophrenia

CRPSCD14IL 6IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin ZonulinAlpha 1 Antitrypsin

Only in Inflammatory Bowel Disease (IBD)

Calprotectin (S100A8/A9)Lactoferrin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Schizophrenia

Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Only in Inflammatory Bowel Disease (IBD)

Alpha Defensins

Ecological state

0 shared

Shared

None indexed

Only in Schizophrenia

SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Only in Inflammatory Bowel Disease (IBD)

Butyrate CollapseBarrier DysfunctionFerroptosisFirmicutes Bacteroidetes Ratio ShiftLPS TranslocationTMAO Elevation

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsBeta-GlucuronidaseIndoleamine 2 3 DioxygenaseTryptophanase

Only in Inflammatory Bowel Disease (IBD)

SiderophoresFimH AdhesinOuter Membrane VesiclesZinc Metalloprotease BFTMucinase