Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

18%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

SchizophreniaandEpilepsy

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

46: Schizophrenia references
9: Epilepsy references
0: shared references

Metals elevated or accumulated

2 shared

Shared

Copper Arsenic

Only in Schizophrenia

Iron Lead Cadmium

Only in Epilepsy

None indexed

Metals depleted or redistributed

1 shared

Taxa enriched

3 shared

Shared

Prevotella Streptococcus Veillonella

Only in Schizophrenia

Lactobacillus EnterobacteriaceaeSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria Prevotellaceae

Only in Epilepsy

Akkermansia muciniphila Enterococcus

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Roseburia Blautia

Only in Schizophrenia

Coprococcus Saccharomyces cerevisiae Bifidobacterium Desulfovibrio Veillonellaceae Lachnospiraceae

Only in Epilepsy

Bacteroides Bacteroides fragilis

Host response elevated

3 shared

Shared

IL 6IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Schizophrenia

CRPSCD14IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin Hepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Only in Epilepsy

Calprotectin (S100A8/A9)

Host response depleted

0 shared

Shared

None indexed

Only in Schizophrenia

Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Only in Epilepsy

Butyrate GABA (Gamma-Aminobutyric Acid)

Ecological state

1 shared

Shared

SCFA Depletion

Only in Schizophrenia

Gut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Only in Epilepsy

Oral Gut TranslocationMucin DegradationKynurenine Pathway ShuntingNeuroinflammation

Virulence and functional enzymes

1 shared

Shared

Tryptophanase

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsBeta-GlucuronidaseIndoleamine 2 3 Dioxygenase

Only in Epilepsy

Beta GlucosidaseIndoleamine 2 3 Dioxygenase Upregulation