Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

14%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Inflammatory Bowel Disease (IBD)andChronic Kidney Disease

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

19: Inflammatory Bowel Disease (IBD) references
34: Chronic Kidney Disease references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Inflammatory Bowel Disease (IBD)

Iron MucosalCopper

Only in Chronic Kidney Disease

Cadmium Lead Arsenic Mercury Chromium NickelIron In Tubular CellsThallium

Metals depleted or redistributed

2 shared

Taxa enriched

2 shared

Shared

Escherichia coli Enterobacteriaceae

Only in Inflammatory Bowel Disease (IBD)

Fusobacterium nucleatum Ruminococcus gnavus

Only in Chronic Kidney Disease

Eggerthella lenta Desulfovibrionales Flavonifractor CollinsellaClostridiaceaeMethanobacteriaParabacteroides Clostridium Ruminococcus Lactobacillus Pseudomonas aeruginosa

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Roseburia Blautia Bifidobacterium Prevotella

Only in Inflammatory Bowel Disease (IBD)

Lachnospiraceae (Family)

Only in Chronic Kidney Disease

Lachnospira Coprococcus Akkermansia muciniphila Eubacterium rectale Ruminococcus bromii Anaerostipes Lachnospiraceae

Host response elevated

2 shared

Shared

Hepcidin Lipocalin-2

Only in Inflammatory Bowel Disease (IBD)

Calprotectin (S100A8/A9)Lactoferrin

Only in Chronic Kidney Disease

CRPIL 6IL 18TNF-alpha (Tumor Necrosis Factor Alpha)TLR2 TLR4NF KappaBNLRP3 InflammasomeSCD14Free Light Chains KappaFree Light Chains LambdaIndoxyl SulfateP Cresyl SulfateTrimethylamine N-Oxide (TMAO)MalondialdehydeUric AcidFerritin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Inflammatory Bowel Disease (IBD)

Alpha Defensins

Only in Chronic Kidney Disease

Alpha-Klotho ButyratePropionateAcetateIndole Propionic AcidTaurineBCAAsVitamin DTotal Antioxidant CapacityENOSGPX4

Ecological state

1 shared

Shared

Ferroptosis

Only in Inflammatory Bowel Disease (IBD)

Butyrate CollapseBarrier DysfunctionFirmicutes Bacteroidetes Ratio ShiftLPS TranslocationTMAO Elevation

Only in Chronic Kidney Disease

Saccharolytic To Proteolytic ShiftSCFA DepletionGut Barrier DysfunctionUremic Toxin AccumulationAmmonia PH DisruptionMetal Microbiome Co ResistanceAntibiotic Resistance Gene EnrichmentVicious Cycle BidirectionalConstipation As Progression MarkerVicious Cycle Metal AccumulationStage 3b Ecological TransitionUremic Toxin ProductionMetal Antibiotic Co ResistanceGut Barrier DisruptionDialysis Irreversibility

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Inflammatory Bowel Disease (IBD)

FimH AdhesinOuter Membrane VesiclesZinc Metalloprotease BFTMucinase

Only in Chronic Kidney Disease

UreaseTryptophanaseTyrosine DecarboxylaseTMA LyaseAromatic Amino Acid Degradation EnzymesBeta-GlucuronidaseHydrogen Sulfide SynthaseCadA Cadmium ATPaseArsC Arsenate ReductaseP Cresyl Sulfate SynthaseIndoxyl Sulfate Synthase