Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

20%: weighted overlap
16: shared signals

First condition

Second condition

Comparison

HypertensionandSchizophrenia

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

14: Hypertension references
46: Schizophrenia references
0: shared references

Metals elevated or accumulated

2 shared

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Hypertension

Magnesium

Only in Schizophrenia

Glutathione (GSH)

Taxa enriched

3 shared

Shared

Enterobacteriaceae Streptococcus Prevotella

Only in Hypertension

Klebsiella pneumoniae Eggerthella Malassezia

Only in Schizophrenia

Lactobacillus VeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria Prevotellaceae

Taxa depleted

4 shared

Shared

Roseburia Faecalibacterium prausnitzii Lachnospiraceae Bifidobacterium

Only in Hypertension

Mortierella

Only in Schizophrenia

Coprococcus Blautia Saccharomyces cerevisiae Desulfovibrio Veillonellaceae

Host response elevated

4 shared

Shared

HepcidinCrpIl 6TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Hypertension

Il 2r AlphaIl 18

Only in Schizophrenia

SCD14IL-1beta (Interleukin-1 Beta)IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Hypertension

Sod

Only in Schizophrenia

Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Ecological state

1 shared

Shared

SCFA Depletion

Only in Hypertension

Elevated Firmicutes Bacteroidetes RatioTMAO ElevationFungal DysbiosisLPS Driven EndotoxemiaBile Acid Disruption

Only in Schizophrenia

Gut Barrier DysfunctionTryptophan Kynurenine ShuntingTranskingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Hypertension

TMA Lyases CutC CutDSiderophoresLPS Biosynthesis EnzymesFungal Lipases

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsBeta-GlucuronidaseIndoleamine 2 3 DioxygenaseTryptophanase