Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
11: shared signals

First condition

Second condition

Comparison

EpilepsyandColorectal Cancer

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Epilepsy references
36: Colorectal Cancer references
0: shared references

Metals elevated or accumulated

2 shared

Shared

Copper Arsenic

Only in Epilepsy

None indexed

Only in Colorectal Cancer

Iron Zinc Cadmium Lead Nickel Chromium

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Akkermansia muciniphila

Only in Epilepsy

Streptococcus Enterococcus Prevotella Veillonella

Only in Colorectal Cancer

Fusobacterium nucleatum Fusobacterium varium Bacteroides fragilis Parvimonas micra Peptostreptococcus stomatis Escherichia coli Clostridium symbiosum Porphyromonas gingivalis Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Taxa depleted

2 shared

Shared

Faecalibacterium prausnitzii Roseburia

Only in Epilepsy

Bacteroides Blautia Bacteroides fragilis

Only in Colorectal Cancer

Lachnospiraceae Prevotella copri Ruminococcus albus Dialister Bifidobacterium Lactobacillus Ruminococcus

Host response elevated

4 shared

Shared

Calprotectin (S100A8/A9)IL-1beta (Interleukin-1 Beta)IL 6TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Epilepsy

None indexed

Only in Colorectal Cancer

Lipopolysaccharide Hepcidin Lipocalin-2

Host response depleted

0 shared

Shared

None indexed

Only in Epilepsy

Butyrate GABA (Gamma-Aminobutyric Acid)

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione PeroxidaseGlutathione (GSH)

Ecological state

1 shared

Shared

SCFA Depletion

Only in Epilepsy

Oral Gut TranslocationMucin DegradationKynurenine Pathway ShuntingNeuroinflammation

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Epilepsy

Beta GlucosidaseTryptophanaseIndoleamine 2 3 Dioxygenase Upregulation

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksSiderophores Urease Glyoxalase I Beta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase