Anxiety Disorders
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This knowledge-base record is being expanded from WikiBiome’s evidence graph.
A neurodevelopmental condition affecting approximately 1 in 36 children (US CDC 2023 estimate), characterized by differences in social communication, restricted interests, and repetitive behaviors. From a metallomics perspective, ASD presents a compelling convergence of…
Premenstrual Dysphoric Disorder (PMDD) affects 3-8% of menstruating individuals Epperson et al. 2012, causing severe mood disturbances, irritability, anxiety, and physical symptoms during the luteal phase of the menstrual cycle. Distinguished from premenstrual syndrome …
The most common form of dementia, affecting an estimated 55 million people worldwide and projected to triple by 2050 zhang 2024 recent advances alzheimers mechanisms trials. Characterized by progressive memory loss, cognitive decline, amyloid-beta plaques, and neurofibr…
Cerebral palsy (CP) is the most common motor disability in childhood, affecting 2-3 per 1,000 live births allen 2021 multi organ dysfunction cerebral palsy. Characterized by non-progressive disturbances in movement and posture arising from injury to the developing brain…
Depression is the most prevalent mental health disorder globally, affecting over 280 million people zhu 2025 microbiota gut brain axis depression review, and one of the most metal-sensitive conditions in this wiki. It sits at the convergence of nearly every pathway cata…
This knowledge-base record is being expanded from WikiBiome’s evidence graph.
Erectile dysfunction (ED) affects 30-50% of men aged 40-70 Feldman et al. 1994, with prevalence increasing with age. Conventionally understood as a vascular and/or neurogenic disorder, ED is now recognized as a condition with a significant gut microbiome component -- th…
Fibromyalgia (FM) is a chronic pain syndrome affecting 2-4% of the global population Heidari et al. 2017, characterized by widespread musculoskeletal pain, fatigue, cognitive dysfunction ("fibro fog"), and sleep disturbances. Conventionally attributed to central sensiti…
A functional gastrointestinal disorder affecting 10-15% of the global population, characterized by chronic abdominal pain, bloating, and altered bowel habits (diarrhea-predominant, constipation-predominant, or mixed) without identifiable structural pathology. From a met…
The second most common neurodegenerative disease, affecting over 10 million people worldwide dorsey 2018 parkinsons incidence meta analysis. Characterized by progressive loss of dopaminergic neurons in the substantia nigra, alpha-synuclein aggregation (Lewy bodies), and…
A metabolic-endocrine disorder affecting 6-20% of reproductive-age women worldwide, characterized by hyperandrogenism, oligo/anovulation, and polycystic ovary morphology (Rotterdam criteria) barrea 2019 mediterranean diet pcos. PCOS is the leading cause of anovulatory i…
A severe neuropsychiatric disorder affecting approximately 1% of the global population, characterized by positive symptoms (hallucinations, delusions), negative symptoms (anhedonia, social withdrawal, flat affect), and cognitive deficits. Life expectancy is reduced by 1…