Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

22%: weighted overlap
17: shared signals

First condition

Second condition

Comparison

SchizophreniaandAnxiety Disorders

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

46: Schizophrenia references
12: Anxiety Disorders references
1: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Schizophrenia

Iron Lead Cadmium Arsenic

Only in Anxiety Disorders

None indexed

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Prevotellaceae

Only in Schizophrenia

Lactobacillus Prevotella Enterobacteriaceae Streptococcus VeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria

Only in Anxiety Disorders

Collinsella Escherichia coli

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Roseburia Blautia Bifidobacterium Lachnospiraceae

Only in Schizophrenia

Coprococcus Saccharomyces cerevisiae Desulfovibrio Veillonellaceae

Only in Anxiety Disorders

Lactobacillus

Host response elevated

4 shared

Shared

CRPIL 6IL-1beta (Interleukin-1 Beta)TNF-alpha (Tumor Necrosis Factor Alpha)

Only in Schizophrenia

SCD14IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin Hepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Only in Anxiety Disorders

Cortisol

Host response depleted

0 shared

Shared

None indexed

Only in Schizophrenia

Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Only in Anxiety Disorders

Butyrate Serotonin GABA (Gamma-Aminobutyric Acid)BDNF (Brain-Derived Neurotrophic Factor)

Ecological state

3 shared

Shared

SCFA DepletionGut Barrier DysfunctionTryptophan Kynurenine Shunting

Only in Schizophrenia

Transkingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Only in Anxiety Disorders

HPA Axis DysregulationVagal Signaling Disruption

Virulence and functional enzymes

2 shared

Shared

Indoleamine 2 3 DioxygenaseTryptophanase

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsBeta-Glucuronidase

Only in Anxiety Disorders

LPS Biosynthesis Enzymes