Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

16%: weighted overlap
13: shared signals

First condition

Second condition

Comparison

Cardiovascular DiseaseandFibromyalgia

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

24: Cardiovascular Disease references
9: Fibromyalgia references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Cardiovascular Disease

Nickel Lead Cadmium Iron

Only in Fibromyalgia

None indexed

Metals depleted or redistributed

3 shared

Taxa enriched

2 shared

Shared

Streptococcus Eggerthella lenta

Only in Cardiovascular Disease

Enterobacteriaceae Escherichia coli Bacteroides fragilis Porphyromonas gingivalis Ruminococcus gnavus Candida albicans Malassezia

Only in Fibromyalgia

Eggerthella Flavonifractor Coprococcus CollinsellaCoprococcus 2

Taxa depleted

3 shared

Shared

Roseburia Faecalibacterium prausnitzii Lachnospiraceae

Only in Cardiovascular Disease

Allisonella Clostridium Clostridiales Mycobiome

Only in Fibromyalgia

Bifidobacterium Bacteroides vulgatus Bacteroides uniformis

Host response elevated

1 shared

Shared

Ceruloplasmin

Only in Cardiovascular Disease

Calprotectin (S100A8/A9)Transferrin Hepcidin Lipocalin-2Lipopolysaccharide LPS

Only in Fibromyalgia

Pro Inflammatory CytokinesCopperSerum ButyrateTNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Host response depleted

2 shared

Shared

Glutathione (GSH)Selenium

Only in Cardiovascular Disease

ButyratePropionateAcetateSelenoproteinsGlutathione Peroxidase

Only in Fibromyalgia

GPX3Ferritin IronGlutathione Peroxidase 3Serotonin

Ecological state

0 shared

Shared

None indexed

Only in Cardiovascular Disease

HypoxiaTMAO Production DominanceLPS EndotoxemiaIndoxyl Sulfate AccumulationReduced Butyrate EcosystemFunctional ShieldingOral To Gut TranslocationBiofilm EndotoxemiaOral Gut TranslocationTMAO AccumulationFungal Bacterial Co Dysbiosis

Only in Fibromyalgia

SCFA DepletionButyrate ParadoxBarrier DysfunctionTryptophan Kynurenine ShuntingCopper Iron Axis ImbalanceCentral SensitizationGut Barrier Dysfunction

Virulence and functional enzymes

1 shared

Shared

Tryptophanase

Only in Cardiovascular Disease

TMA Lyase CutC/DLipopolysaccharide LPS BiosynthesisSiderophores Enterobactin YersiniabactinBeta-GlucuronidaseIndole ProductionHSP60TMA Lyase CutC CutDLPS Biosynthesis EnzymesSiderophores

Only in Fibromyalgia

Pro Inflammatory Metabolite SynthesisCopper Dependent OxidasesIndoleamine 2 3 DioxygenaseLPS BiosynthesisNeurotoxic Metabolite Production