Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

22%: weighted overlap
17: shared signals

First condition

Second condition

Comparison

Anxiety DisordersandSchizophrenia

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

12: Anxiety Disorders references
46: Schizophrenia references
1: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Anxiety Disorders

None indexed

Only in Schizophrenia

Iron Lead Cadmium Arsenic

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Prevotellaceae

Only in Anxiety Disorders

Collinsella Escherichia coli

Only in Schizophrenia

Lactobacillus Prevotella Enterobacteriaceae Streptococcus VeillonellaSuccinivibrioCandida albicansTrichosporonPurpureocillium Clostridia Betaproteobacteria

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium Blautia Lachnospiraceae

Only in Anxiety Disorders

Lactobacillus

Only in Schizophrenia

Coprococcus Saccharomyces cerevisiae Desulfovibrio Veillonellaceae

Host response elevated

4 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)IL 6IL-1beta (Interleukin-1 Beta)CRP

Only in Anxiety Disorders

Cortisol

Only in Schizophrenia

SCD14IL-8 (Interleukin-8 / CXCL8)IL 12TGF-beta (Transforming Growth Factor Beta)NLRP3 InflammasomeComplement C4AMalondialdehydeCeruloplasmin Bound CopperCeruloplasmin Hepcidin Lipocalin-2 ZonulinAlpha 1 Antitrypsin

Host response depleted

0 shared

Shared

None indexed

Only in Anxiety Disorders

Butyrate Serotonin GABA (Gamma-Aminobutyric Acid)BDNF (Brain-Derived Neurotrophic Factor)

Only in Schizophrenia

Glutathione (GSH)Total Antioxidant CapacityVitamin DAnti Inflammatory CytokinesSCFAsZinc Finger Proteins

Ecological state

3 shared

Shared

SCFA DepletionTryptophan Kynurenine ShuntingGut Barrier Dysfunction

Only in Anxiety Disorders

HPA Axis DysregulationVagal Signaling Disruption

Only in Schizophrenia

Transkingdom Network DisruptionOral Gut Axis H2S EnrichmentMulti Kingdom DysbiosisMetabolic Syndrome ComorbidityGut Barrier DisruptionMicroglial ActivationTh17 Treg ImbalanceVirome Dysbiosis

Virulence and functional enzymes

2 shared

Shared

Indoleamine 2 3 DioxygenaseTryptophanase

Only in Anxiety Disorders

LPS Biosynthesis Enzymes

Only in Schizophrenia

Tryptophan Catabolism EnzymesH2S Producing Enzyme SystemsLPS BiosynthesisSiderophore SystemsBeta-Glucuronidase