Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

14%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

Anxiety DisordersandColorectal Cancer

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

12: Anxiety Disorders references
36: Colorectal Cancer references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Copper

Only in Anxiety Disorders

None indexed

Only in Colorectal Cancer

Iron Zinc Cadmium Lead Nickel Arsenic Chromium

Metals depleted or redistributed

1 shared

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Anxiety Disorders

Collinsella Prevotellaceae

Only in Colorectal Cancer

Fusobacterium nucleatum Fusobacterium varium Bacteroides fragilis Parvimonas micra Peptostreptococcus stomatis Clostridium symbiosum Porphyromonas gingivalis Akkermansia muciniphila Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium Lactobacillus Lachnospiraceae

Only in Anxiety Disorders

Blautia

Only in Colorectal Cancer

Prevotella copri Ruminococcus albus Dialister Ruminococcus

Host response elevated

3 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)IL 6IL-1beta (Interleukin-1 Beta)

Only in Anxiety Disorders

CortisolCRP

Only in Colorectal Cancer

Lipopolysaccharide Calprotectin (S100A8/A9)Hepcidin Lipocalin-2

Host response depleted

0 shared

Shared

None indexed

Only in Anxiety Disorders

Butyrate Serotonin GABA (Gamma-Aminobutyric Acid)BDNF (Brain-Derived Neurotrophic Factor)

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione PeroxidaseGlutathione (GSH)

Ecological state

1 shared

Shared

SCFA Depletion

Only in Anxiety Disorders

Tryptophan Kynurenine ShuntingHPA Axis DysregulationVagal Signaling DisruptionGut Barrier Dysfunction

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Anxiety Disorders

Indoleamine 2 3 DioxygenaseTryptophanaseLPS Biosynthesis Enzymes

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksSiderophores Urease Glyoxalase I Beta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase