Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 26%
- weighted overlap
- 25
- shared signals
Comparison
Type 2 DiabetesandAlzheimer's Disease
2 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 30
- Type 2 Diabetes references
- 31
- Alzheimer's Disease references
- 2
- shared references
Metals depleted or redistributed
2 sharedTaxa enriched
4 sharedShared
Only in Type 2 Diabetes
Only in Alzheimer's Disease
Taxa depleted
5 sharedShared
Only in Type 2 Diabetes
Only in Alzheimer's Disease
Host response elevated
1 sharedShared
Only in Type 2 Diabetes
LipopolysaccharideInflammatory CytokinesTNF-alpha (Tumor Necrosis Factor Alpha)IL 6FerritinCeruloplasmin
Only in Alzheimer's Disease
Lipocalin-2Calprotectin (S100A8/A9)Proinflammatory CytokinesTransferrin Receptor AlteredFerritin AlteredTREM2
Host response depleted
3 sharedEcological state
2 sharedShared
DysbiosisSCFA Depletion
Only in Type 2 Diabetes
LPS ElevationBile Acid DysmetabolismImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth
Only in Alzheimer's Disease
HypoxiaBarrier DysfunctionNeuroinflammationAmyloid SeedingMicroglial ActivationLPS TranslocationBlood Brain Barrier DisruptionAmyloid Cross SeedingLPS EndotoxemiaTMAO ElevationFerroptosisEpigenetic Latency
Virulence and functional enzymes
3 sharedShared
Only in Type 2 Diabetes
Choline TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesLPS Biosynthesis EnzymesTMA Lyase CutC CutD