Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

6%: weighted overlap
5: shared signals

First condition

Second condition

Comparison

Necrotizing EnterocolitisandGraves' Disease

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

19: Necrotizing Enterocolitis references
22: Graves' Disease references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Iron

Only in Necrotizing Enterocolitis

None indexed

Only in Graves' Disease

LeadIodine DysregulatedCadmium Mercury

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Necrotizing Enterocolitis

None indexed

Only in Graves' Disease

Selenium Iron

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Necrotizing Enterocolitis

Klebsiella Clostridium perfringens Staphylococcus Klebsiella pneumoniaeClostridium Perfringens (Toxigenic)Sphingomonas Spp.Clostridium Spp. (Obligate Anaerobe Cluster)Bacteroides/Prevotella (Obligate Anaerobe Cluster)Staphylococcus epidermidis Enterococcus

Only in Graves' Disease

Bacteroides fragilis Enterobacteriaceae Streptococcus Prevotella Lactobacillus Collinsella Bifidobacterium Desulfovibrio Veillonella

Taxa depleted

1 shared

Host response elevated

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

Calprotectin (S100A8/A9)Lactoferrin EndogenousPro Inflammatory CytokinesTLR4 ExpressionLPSTNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IL 6

Only in Graves' Disease

Hepcidin Transferrin Lipocalin-2

Host response depleted

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

Zinc Defensins AcetateLactateSecretory IgA

Only in Graves' Disease

SelenoproteinsGlutathione PeroxidaseThioredoxin ReductaseDeiodinases

Ecological state

0 shared

Shared

None indexed

Only in Necrotizing Enterocolitis

Proteobacteria Bloom 2 Weeks Pre DiagnosisVirome Convergence 10 Days Pre OnsetTLR4 Upregulation In Premature EpitheliumBifidobacterium Absence As PreconditionHMO Mediated Colonization ResistanceFeed Forward Barrier DestructionProteobacteria BloomTLR4 Feed Forward LoopVirome ConvergenceImmature BarrierParenteral Iron OverloadBiofilmBile Acid Accumulation ASBT UpregulationMuc2 Depletion Mucosal Barrier FailureObligate Anaerobe Mucosal InvasionGut Brain Axis NDI RiskAntibiotic Driven Richness Nadir Week4

Only in Graves' Disease

Intestinal PermeabilityTh17 Treg ImbalanceMolecular Mimicry Estrogen RecirculationSCFA DeficiencyLPS TranslocationBidirectional Gut Thyroid Axis

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Necrotizing Enterocolitis

LPS BiosynthesisAlpha ToxinPerfringolysin OBiofilm Formation Enzymes

Only in Graves' Disease

Beta-GlucuronidaseLPSThyroid Peroxidase Mimicry AntigensLPS Endotoxin