Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

17%: weighted overlap
18: shared signals

First condition

Second condition

Comparison

Long COVIDandCardiovascular Disease

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

18: Long COVID references
24: Cardiovascular Disease references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Long COVID

Zinc Arsenic Thallium

Only in Cardiovascular Disease

Nickel Lead Cadmium Iron Copper

Metals depleted or redistributed

3 shared

Taxa enriched

4 shared

Shared

Enterobacteriaceae Streptococcus Candida albicans Escherichia coli

Only in Long COVID

Enterococcus Veillonella Fusobacterium nucleatum Aspergillus Klebsiella pneumoniae

Only in Cardiovascular Disease

Bacteroides fragilis Porphyromonas gingivalis Eggerthella lenta Ruminococcus gnavus Malassezia

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Roseburia Lachnospiraceae

Only in Long COVID

Bifidobacterium Lactobacillus Akkermansia muciniphila

Only in Cardiovascular Disease

Allisonella Clostridium Clostridiales Mycobiome

Host response elevated

2 shared

Shared

Hepcidin Calprotectin (S100A8/A9)

Only in Long COVID

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesZinc In Secretions

Only in Cardiovascular Disease

Transferrin Lipocalin-2Lipopolysaccharide LPSCeruloplasmin

Host response depleted

3 shared

Shared

Glutathione (GSH)Butyrate Selenium

Only in Long COVID

Regulatory T CellsNK Cell FunctionMemory B CellsSIgAIron In Tissues

Only in Cardiovascular Disease

PropionateAcetateSelenoproteinsGlutathione Peroxidase

Ecological state

0 shared

Shared

None indexed

Only in Long COVID

Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBarrier DysfunctionBacterial TranslocationMulti Kingdom Co DysbiosisSCFA DepletionNon Linear Recovery

Only in Cardiovascular Disease

HypoxiaTMAO Production DominanceLPS EndotoxemiaIndoxyl Sulfate AccumulationReduced Butyrate EcosystemFunctional ShieldingOral To Gut TranslocationBiofilm EndotoxemiaOral Gut TranslocationTMAO AccumulationFungal Bacterial Co Dysbiosis

Virulence and functional enzymes

3 shared

Shared

Siderophores Beta-GlucuronidaseLPS Biosynthesis Enzymes

Only in Long COVID

LPS Synthesis TransportAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Polysaccharide DegradationBeta Lactamases

Only in Cardiovascular Disease

TMA Lyase CutC/DLipopolysaccharide LPS BiosynthesisSiderophores Enterobactin YersiniabactinTryptophanaseIndole ProductionHSP60TMA Lyase CutC CutD