Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Cerebral PalsyandDepression

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Cerebral Palsy references
38: Depression references
0: shared references

Metals elevated or accumulated

2 shared

Metals depleted or redistributed

2 shared

Shared

Iron Zinc

Only in Cerebral Palsy

None indexed

Only in Depression

Magnesium Selenium

Taxa enriched

0 shared

Shared

None indexed

Only in Cerebral Palsy

Streptococcus Enterococcus Akkermansia muciniphila Prevotella Veillonella Klebsiella Klebsiella pneumoniae Fusobacterium

Only in Depression

Candida albicans Clostridium Bacteroides fragilis Escherichia coli Eggerthella Enterobacteriaceae Flavonifractor

Taxa depleted

2 shared

Shared

Faecalibacterium prausnitzii Lactobacillus

Only in Cerebral Palsy

Bacteroides Blautia Ruminococcus Roseburia Bacteroides fragilis

Only in Depression

Bifidobacterium Lachnospiraceae Prevotella Coprococcus Dialister

Host response elevated

3 shared

Shared

Pro Inflammatory CytokinesCalprotectin (S100A8/A9)Hepcidin

Only in Cerebral Palsy

TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IL 6IL-8 (Interleukin-8 / CXCL8)IL-10 (Interleukin-10)

Only in Depression

Ceruloplasmin Ferritin

Host response depleted

2 shared

Shared

Iron Zinc

Only in Cerebral Palsy

Butyrate Vitamin D

Only in Depression

Magnesium Selenium Glutathione (GSH)Glutathione Peroxidase

Ecological state

1 shared

Shared

SCFA Depletion

Only in Cerebral Palsy

NEC To CP PathwayTLR4 LPS Microglial ActivationOral Gut Inflammatory AxisWhite Matter InjuryProteobacteria BloomKynurenine Pathway DysregulationOral Gut TranslocationMucin DegradationConstipation Driven Oxygen ShiftBiofilm

Only in Depression

DysbiosisLeaky GutIntestinal Permeability EndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOHPA Axis HyperactivationBlood Brain Barrier DisruptionNeuroinflammation

Virulence and functional enzymes

2 shared

Shared

LPS BiosynthesisTryptophanase

Only in Cerebral Palsy

SiderophoresTLR4 LPS SignalingBeta Glucosidase

Only in Depression

Beta-GlucuronidasePro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli