Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

17%: weighted overlap
18: shared signals

First condition

Second condition

Comparison

Cardiovascular DiseaseandLong COVID

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

24: Cardiovascular Disease references
18: Long COVID references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Cardiovascular Disease

Nickel Lead Cadmium Iron Copper

Only in Long COVID

Zinc Arsenic Thallium

Metals depleted or redistributed

3 shared

Taxa enriched

4 shared

Shared

Enterobacteriaceae Escherichia coli Streptococcus Candida albicans

Only in Cardiovascular Disease

Bacteroides fragilis Porphyromonas gingivalis Eggerthella lenta Ruminococcus gnavus Malassezia

Only in Long COVID

Enterococcus Veillonella Fusobacterium nucleatum Aspergillus Klebsiella pneumoniae

Taxa depleted

3 shared

Shared

Roseburia Faecalibacterium prausnitzii Lachnospiraceae

Only in Cardiovascular Disease

Allisonella Clostridium Clostridiales Mycobiome

Only in Long COVID

Bifidobacterium Lactobacillus Akkermansia muciniphila

Host response elevated

2 shared

Shared

Calprotectin (S100A8/A9)Hepcidin

Only in Cardiovascular Disease

Transferrin Lipocalin-2Lipopolysaccharide LPSCeruloplasmin

Only in Long COVID

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesZinc In Secretions

Host response depleted

3 shared

Shared

Glutathione (GSH)Butyrate Selenium

Only in Cardiovascular Disease

PropionateAcetateSelenoproteinsGlutathione Peroxidase

Only in Long COVID

Regulatory T CellsNK Cell FunctionMemory B CellsSIgAIron In Tissues

Ecological state

0 shared

Shared

None indexed

Only in Cardiovascular Disease

HypoxiaTMAO Production DominanceLPS EndotoxemiaIndoxyl Sulfate AccumulationReduced Butyrate EcosystemFunctional ShieldingOral To Gut TranslocationBiofilm EndotoxemiaOral Gut TranslocationTMAO AccumulationFungal Bacterial Co Dysbiosis

Only in Long COVID

Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBarrier DysfunctionBacterial TranslocationMulti Kingdom Co DysbiosisSCFA DepletionNon Linear Recovery

Virulence and functional enzymes

3 shared

Shared

Beta-GlucuronidaseLPS Biosynthesis EnzymesSiderophores

Only in Cardiovascular Disease

TMA Lyase CutC/DLipopolysaccharide LPS BiosynthesisSiderophores Enterobactin YersiniabactinTryptophanaseIndole ProductionHSP60TMA Lyase CutC CutD

Only in Long COVID

LPS Synthesis TransportAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Polysaccharide DegradationBeta Lactamases