Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

FibromyalgiaandLong COVID

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Fibromyalgia references
18: Long COVID references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Fibromyalgia

Copper

Only in Long COVID

Zinc Arsenic Thallium

Metals depleted or redistributed

3 shared

Taxa enriched

1 shared

Shared

Streptococcus

Only in Fibromyalgia

Eggerthella Flavonifractor Coprococcus Collinsella Eggerthella lentaCoprococcus 2

Only in Long COVID

Enterobacteriaceae Enterococcus Veillonella Candida albicans Fusobacterium nucleatum Aspergillus Escherichia coli Klebsiella pneumoniae

Taxa depleted

4 shared

Shared

Faecalibacterium prausnitzii Bifidobacterium Lachnospiraceae Roseburia

Only in Fibromyalgia

Bacteroides vulgatus Bacteroides uniformis

Only in Long COVID

Lactobacillus Akkermansia muciniphila

Host response elevated

2 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Only in Fibromyalgia

CeruloplasminPro Inflammatory CytokinesCopperSerum Butyrate

Only in Long COVID

IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesHepcidin Calprotectin (S100A8/A9)Zinc In Secretions

Host response depleted

2 shared

Shared

Glutathione (GSH)Selenium

Only in Fibromyalgia

GPX3Ferritin IronGlutathione Peroxidase 3Serotonin

Only in Long COVID

Regulatory T CellsNK Cell FunctionMemory B CellsSIgAButyrateIron In Tissues

Ecological state

2 shared

Shared

SCFA DepletionBarrier Dysfunction

Only in Fibromyalgia

Butyrate ParadoxTryptophan Kynurenine ShuntingCopper Iron Axis ImbalanceCentral SensitizationGut Barrier Dysfunction

Only in Long COVID

Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBacterial TranslocationMulti Kingdom Co DysbiosisNon Linear Recovery

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Fibromyalgia

TryptophanasePro Inflammatory Metabolite SynthesisCopper Dependent OxidasesIndoleamine 2 3 DioxygenaseLPS BiosynthesisNeurotoxic Metabolite Production

Only in Long COVID

LPS Synthesis TransportSiderophoresAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Beta-GlucuronidasePolysaccharide DegradationLPS Biosynthesis EnzymesBeta Lactamases