Representative Anaerococcus cellular arrangements. The type species A. prevotii is an obligate anaerobic coccus commonly seen in clumps or tetrads; this reconstruction is genus-level and not diagnostic.
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- Anaerococcustaxon · genus
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- NCBITaxon:165779
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- Editorial review completeIdentifiers authority-verified · Accessibility validated · · anaerococcus|anaerococcus-morphology-v1.webp
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Anaerococcus is a genus of Gram-positive, obligate anaerobic cocci within the phylum Firmicutes. It is a normal inhabitant of the human vaginal, skin, and gastrointestinal microbiota, but is recognized as an opportunistic pathogen in dysbiotic states, particularly when Lactobacillus-dominant vaginal communities are disrupted.
Anaerococcus enrichment has been documented in the vaginal microbiome of women with endometriosis, where its increased abundance correlates with non-Lactobacillus-dominant community state types (,[1]The Vaginal Microbiome as a Tool to Predict rASRM Stage of Disease in Endometriosis: a Pilot StudyPerrotta AR, Borrelli GM, Martins CO et al. · 2020Open reference 1 ↓ cross-sectional;,[2]MacSharry 2024 — Endometriosis Specific Vaginal Microbiota Links to Urine and Serum N-GlycomeJohn MacSharry, Zsuzsanna Kovacs, Yongjing Xie et al. · 2024Open reference 2 ↓ cross-sectional).
The genus has also been identified as enriched in HPV-positive cervical cancer, where it contributes to the anaerobic, pro-inflammatory vaginal environment associated with persistent HPV infection and malignant progression (,[3]Rashwan et al. 2025 — Insights into the Tripartite Relationship between Cervical Cancer, HPV, and the Vaginal Microbiome: A Mega-AnalysisRashwan HH, Ali MH, Mostafa MM et al. · 2025Open reference 3 ↓ mega-analysis).
These patterns position Anaerococcus as a marker of vaginal Dysbiosis across gynecological conditions.
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Anaerococcus enrichment has been documented in the vaginal microbiome of women with endometriosis, where its increased abundance correlates with non-Lactobacillus-dominant community state types (, cross-sectional;, cross-sectional). The genus has also been identified as enriched in HPV-positive cervical cancer, where it contributes to the anaerobic, pro-infl
Contents
1. Cross-ReferencesCross-References#
- Bacterial Vaginosis—associated dysbiotic state
- Endometriosis—condition of enrichment
- cervical cancer—condition of enrichment
- Lactobacillus—inversely correlated in vaginal communities
References 3
Numbered by first appearance in the article, then reconciled with its declared source list.
- 1
Perrotta AR, Borrelli GM, Martins CO et al. (2020). The Vaginal Microbiome as a Tool to Predict rASRM Stage of Disease in Endometriosis: a Pilot Study. Reproductive Sciences.
- 2
John MacSharry, Zsuzsanna Kovacs, Yongjing Xie et al. (2024). MacSharry 2024 — Endometriosis Specific Vaginal Microbiota Links to Urine and Serum N-Glycome. Scientific Reports.
- 3
Rashwan HH, Ali MH, Mostafa MM et al. (2025). Rashwan et al. 2025 — Insights into the Tripartite Relationship between Cervical Cancer, HPV, and the Vaginal Microbiome: A Mega-Analysis. Human Genomics.
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Created “Anaerococcus”: Anaerococcus is a genus of Gram-positive, obligate anaerobic cocci within the phylum Firmicutes. It is a normal inhabitant of the human vaginal, skin, and gastrointestinal microbiota, but is…
Created “Anaerococcus”: Anaerococcus is a genus of Gram-positive, obligate anaerobic cocci within the phylum Firmicutes. It is a normal inhabitant of the human vaginal, skin, and gastrointestinal microbiota, but is… Published sections: Anaerococcus; Cross-References. · WikiBiome Deploy Bot · +37 −0
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