Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

13%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

Ovarian CancerandAutism Spectrum Disorder

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

33: Ovarian Cancer references
32: Autism Spectrum Disorder references
1: shared references

Metals elevated or accumulated

3 shared

Shared

Cadmium Nickel Arsenic

Only in Ovarian Cancer

IronIron Tumor

Only in Autism Spectrum Disorder

Lead Mercury Copper

Metals depleted or redistributed

2 shared

Taxa enriched

0 shared

Shared

None indexed

Only in Ovarian Cancer

Escherichia coli Proteobacteria (Pseudomonadota)Propionibacterium Candida albicans Dialister Fusobacterium nucleatum

Only in Autism Spectrum Disorder

Bacteroides Parabacteroides ClostridiumEubacterium CoprostanoligenesDesulfovibrio

Taxa depleted

4 shared

Shared

Lactobacillus Coprococcus Bifidobacterium Faecalibacterium prausnitzii

Only in Ovarian Cancer

Roseburia Butyricicoccus Oscillibacter Saccharomyces cerevisiae

Only in Autism Spectrum Disorder

Lachnospiraceae

Host response elevated

1 shared

Shared

Inflammatory Cytokines

Only in Ovarian Cancer

Tumor Associated MacrophagesLPSLysophosphatidic AcidTRAF3 Immune SuppressionTransferrin Receptor 1

Only in Autism Spectrum Disorder

Calprotectin (S100A8/A9)Lactoferrin Transferrin Hepcidin Lipocalin-2 TNF-alpha (Tumor Necrosis Factor Alpha)IL 1IL 6IL 2IL-17 (Interleukin-17)IFN-gamma (Interferon Gamma)NF KappaBMalondialdehydeFolate Receptor AutoantibodiesPropionic AcidMetallothionein Induced

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Ovarian Cancer

TaurineB Cell IgA ResponseIndole 3 Propionic AcidOmega Oxidation EnzymesSelenium Ferroportin

Only in Autism Spectrum Disorder

SulfateZinc IL-10 (Interleukin-10)TGF-beta (Transforming Growth Factor Beta)NRF2 FunctionZO 1ClaudinsOccludinZinc MetalloenzymesGPx ActivityCu Zn SOD

Ecological state

0 shared

Shared

None indexed

Only in Ovarian Cancer

Multi Compartment OncobiosisSCFA DepletionAscending Infection ModelFerroptosis ResistancePolyamine Biosynthesis UpregulationOxidative Stress ToleranceDiet Microbiome Cancer AxisAntibiotic VulnerabilityTryptophan Kynurenine ShuntingMetalloestrogen Signaling

Only in Autism Spectrum Disorder

Gut Barrier DysfunctionPropionic Acid NeurotoxicityOxidative StressBBB DisruptionDemyelinationExcitatory Inhibitory ImbalanceOne Carbon Metabolism DisruptionSulfate DepletionEarly Antibiotic DisruptionMaternal Microbiome TransmissionMicrobial Zinc CompetitionMetal Profile Not Single MetalGut Barrier DisruptionMis-MetallationPropionic Acid ElevationSCFA ImbalanceNeuroinflammationDevelopmental Vulnerability

Virulence and functional enzymes

1 shared

Shared

Beta-Glucuronidase

Only in Ovarian Cancer

LPS BiosynthesisOxidative Stress Tolerance EnzymesKeap1 Nrf2 GPX4 AxisSiderophores

Only in Autism Spectrum Disorder

ALA Dehydrase Inhibited By PbCNPase Inhibited By PbHydrogen Sulfide ProductionPropionic Acid Production