Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
12: shared signals

First condition

Second condition

Comparison

Cerebral PalsyandAutism Spectrum Disorder

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Cerebral Palsy references
32: Autism Spectrum Disorder references
0: shared references

Metals elevated or accumulated

3 shared

Shared

Lead Arsenic Copper

Only in Cerebral Palsy

None indexed

Only in Autism Spectrum Disorder

Mercury Cadmium Nickel

Metals depleted or redistributed

2 shared

Shared

Iron Zinc

Only in Cerebral Palsy

None indexed

Only in Autism Spectrum Disorder

Glutathione (GSH)Selenium

Taxa enriched

0 shared

Shared

None indexed

Only in Cerebral Palsy

Streptococcus Enterococcus Akkermansia muciniphila Prevotella Veillonella Klebsiella Klebsiella pneumoniae Fusobacterium

Only in Autism Spectrum Disorder

Bacteroides Parabacteroides ClostridiumEubacterium CoprostanoligenesDesulfovibrio

Taxa depleted

2 shared

Host response elevated

4 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)Calprotectin (S100A8/A9)IL 6Hepcidin

Only in Cerebral Palsy

Pro Inflammatory CytokinesIL-1beta (Interleukin-1 Beta)IL-8 (Interleukin-8 / CXCL8)IL-10 (Interleukin-10)

Only in Autism Spectrum Disorder

Lactoferrin Transferrin Lipocalin-2IL 1IL 2IL-17 (Interleukin-17)IFN-gamma (Interferon Gamma)NF KappaBMalondialdehydeFolate Receptor AutoantibodiesPropionic AcidMetallothionein InducedInflammatory Cytokines

Host response depleted

1 shared

Shared

Zinc

Only in Cerebral Palsy

Iron Butyrate Vitamin D

Only in Autism Spectrum Disorder

Glutathione (GSH)SulfateIL-10 (Interleukin-10)TGF-beta (Transforming Growth Factor Beta)NRF2 FunctionZO 1ClaudinsOccludinZinc MetalloenzymesGPx ActivityCu Zn SOD

Ecological state

0 shared

Shared

None indexed

Only in Cerebral Palsy

NEC To CP PathwayTLR4 LPS Microglial ActivationOral Gut Inflammatory AxisWhite Matter InjurySCFA DepletionProteobacteria BloomKynurenine Pathway DysregulationOral Gut TranslocationMucin DegradationConstipation Driven Oxygen ShiftBiofilm

Only in Autism Spectrum Disorder

Gut Barrier DysfunctionPropionic Acid NeurotoxicityOxidative StressBBB DisruptionDemyelinationExcitatory Inhibitory ImbalanceOne Carbon Metabolism DisruptionSulfate DepletionEarly Antibiotic DisruptionMaternal Microbiome TransmissionMicrobial Zinc CompetitionMetal Profile Not Single MetalGut Barrier DisruptionMis-MetallationPropionic Acid ElevationSCFA ImbalanceNeuroinflammationDevelopmental Vulnerability

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Cerebral Palsy

LPS BiosynthesisSiderophoresTryptophanaseTLR4 LPS SignalingBeta Glucosidase

Only in Autism Spectrum Disorder

Beta-GlucuronidaseALA Dehydrase Inhibited By PbCNPase Inhibited By PbHydrogen Sulfide ProductionPropionic Acid Production