Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

14%: weighted overlap
11: shared signals

First condition

Second condition

Comparison

Celiac DiseaseandColorectal Cancer

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

8: Celiac Disease references
36: Colorectal Cancer references
0: shared references

Metals elevated or accumulated

1 shared

Shared

Nickel

Only in Celiac Disease

None indexed

Only in Colorectal Cancer

Iron Zinc Cadmium Lead Copper Arsenic Chromium

Metals depleted or redistributed

2 shared

Taxa enriched

2 shared

Shared

Escherichia coli Bacteroides fragilis

Only in Celiac Disease

Proteobacteria (Pseudomonadota)Staphylococcus aureus

Only in Colorectal Cancer

Fusobacterium nucleatum Fusobacterium varium Parvimonas micra Peptostreptococcus stomatis Clostridium symbiosum Porphyromonas gingivalis Akkermansia muciniphila Candida albicans Peptostreptococcus anaerobius Enterococcus faecalis Streptococcus gallolyticus Saccharomyces cerevisiae

Taxa depleted

4 shared

Shared

Bifidobacterium Lactobacillus Faecalibacterium prausnitzii Lachnospiraceae

Only in Celiac Disease

Prevotella

Only in Colorectal Cancer

Roseburia Prevotella copri Ruminococcus albus Dialister Ruminococcus

Host response elevated

0 shared

Shared

None indexed

Only in Celiac Disease

Zonulin

Only in Colorectal Cancer

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Calprotectin (S100A8/A9)Hepcidin Lipocalin-2

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Celiac Disease

None indexed

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione Peroxidase

Ecological state

0 shared

Shared

None indexed

Only in Celiac Disease

Villous AtrophyIncreased Intestinal PermeabilityGluten Mediated Tight Junction DisassemblyNickel Allergic Contact Mucositis

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessSCFA DepletionWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Virulence and functional enzymes

1 shared

Shared

Beta-Glucuronidase

Only in Celiac Disease

Bacterial ProteasesTissue Transglutaminase 2 Mimicry

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksSiderophores Urease Glyoxalase IBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase