Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

21%: weighted overlap
18: shared signals

First condition

Second condition

Comparison

Type 2 DiabetesandCerebral Palsy

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

30: Type 2 Diabetes references
9: Cerebral Palsy references
0: shared references

Metals elevated or accumulated

2 shared

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Type 2 Diabetes

Chromium Magnesium Glutathione (GSH)Manganese

Only in Cerebral Palsy

Iron

Taxa enriched

3 shared

Shared

Streptococcus Prevotella Enterococcus

Only in Type 2 Diabetes

Escherichia coli Enterobacteriaceae Candida albicans Helicobacter pylori Campylobacter jejuni

Only in Cerebral Palsy

Akkermansia muciniphila Veillonella Klebsiella Klebsiella pneumoniae Fusobacterium

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Ruminococcus Bacteroides fragilis Roseburia Blautia

Only in Type 2 Diabetes

Bifidobacterium Akkermansia muciniphila Lachnospiraceae

Only in Cerebral Palsy

Bacteroides Lactobacillus

Host response elevated

3 shared

Shared

Hepcidin TNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Only in Type 2 Diabetes

LipopolysaccharideInflammatory CytokinesFerritin Ceruloplasmin

Only in Cerebral Palsy

Pro Inflammatory CytokinesIL-1beta (Interleukin-1 Beta)Calprotectin (S100A8/A9)IL-8 (Interleukin-8 / CXCL8)IL-10 (Interleukin-10)

Host response depleted

2 shared

Shared

Butyrate Zinc

Only in Type 2 Diabetes

PropionateAcetateBile AcidsGlutathione (GSH)Chromium Manganese Magnesium

Only in Cerebral Palsy

Iron Vitamin D

Ecological state

1 shared

Shared

SCFA Depletion

Only in Type 2 Diabetes

DysbiosisLPS ElevationBile Acid DysmetabolismImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth

Only in Cerebral Palsy

NEC To CP PathwayTLR4 LPS Microglial ActivationOral Gut Inflammatory AxisWhite Matter InjuryProteobacteria BloomKynurenine Pathway DysregulationOral Gut TranslocationMucin DegradationConstipation Driven Oxygen ShiftBiofilm

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Type 2 Diabetes

LipopolysaccharideCholine TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesLPS Biosynthesis EnzymesNickel-UreaseTMA Lyase CutC CutD

Only in Cerebral Palsy

LPS BiosynthesisTryptophanaseTLR4 LPS SignalingBeta Glucosidase