Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

11%: weighted overlap
8: shared signals

First condition

Second condition

Comparison

ObesityandUlcerative Colitis

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

31: Obesity references
6: Ulcerative Colitis references
1: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Obesity

Cadmium Nickel Lead Manganese Zinc Iron

Only in Ulcerative Colitis

CopperIron LuminalThallium

Metals depleted or redistributed

0 shared

Shared

None indexed

Only in Obesity

Glutathione (GSH)Magnesium Barium Vanadium Titanium

Only in Ulcerative Colitis

Iron SystemicZinc Selenium Manganese

Taxa enriched

1 shared

Taxa depleted

3 shared

Shared

Faecalibacterium prausnitzii Roseburia Lachnospiraceae

Only in Obesity

Akkermansia muciniphila Bifidobacterium Oscillospiraceae

Only in Ulcerative Colitis

Bacteroides

Host response elevated

3 shared

Shared

Hepcidin Calprotectin (S100A8/A9)Lactoferrin

Only in Obesity

Transferrin Lipocalin-2 Ferritin

Only in Ulcerative Colitis

Ceruloplasmin Copper

Host response depleted

0 shared

Shared

None indexed

Only in Obesity

Glutathione (GSH)Butyrate Short-Chain Fatty Acids (SCFAs)

Only in Ulcerative Colitis

Zinc SeleniumGlutathione Peroxidase

Ecological state

0 shared

Shared

None indexed

Only in Obesity

HypoxiaMetal Driven DysbiosisReduced SCFA ProductionIncreased LPSEndotoxemiaIntestinal Permeability IncreaseFermentative Metabolism Acidic MicroenvironmentMetabolic EndotoxemiaReduced Microbial DiversityIncreased Energy HarvestBile Acid DysregulationVirome Depletion

Only in Ulcerative Colitis

Iron Pathobiont Feedback LoopButyrate DepletionMucosal UlcerationBarrier DysfunctionTh17 Treg ImbalanceMucin Degradation

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Obesity

TMA LyaseNickel-UreaseNickel HydrogenaseZinc MetalloproteasesLPS BiosynthesisBeta-Glucuronidase

Only in Ulcerative Colitis

Iron Acquisition SystemsAdhesinsMucin Degrading Glycosidases