Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Long COVIDandHashimoto's Thyroiditis

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

18: Long COVID references
17: Hashimoto's Thyroiditis references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Long COVID

Zinc Arsenic Thallium

Only in Hashimoto's Thyroiditis

Iodine ExcessCadmium Lead Mercury Nickel Copper

Metals depleted or redistributed

2 shared

Taxa enriched

1 shared

Shared

Klebsiella pneumoniae

Only in Long COVID

Enterobacteriaceae Streptococcus Enterococcus Veillonella Candida albicans Fusobacterium nucleatum Aspergillus Escherichia coli

Only in Hashimoto's Thyroiditis

Proteobacteria (Pseudomonadota)Actinobacteria (Actinomycetota)Blautia Dorea Prevotella Akkermansia muciniphila Bifidobacterium Intestinimonas Turicibacter

Taxa depleted

6 shared

Shared

Faecalibacterium prausnitzii Roseburia Bifidobacterium Lactobacillus Akkermansia muciniphila Lachnospiraceae

Only in Long COVID

None indexed

Only in Hashimoto's Thyroiditis

Coprococcus

Host response elevated

2 shared

Shared

Hepcidin Calprotectin (S100A8/A9)

Only in Long COVID

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesZinc In Secretions

Only in Hashimoto's Thyroiditis

CeruloplasminAdvanced Glycation End Products

Host response depleted

1 shared

Shared

Butyrate

Only in Long COVID

Regulatory T CellsNK Cell FunctionMemory B CellsSIgAGlutathione (GSH)SeleniumIron In Tissues

Only in Hashimoto's Thyroiditis

Selenium Dependent GPxSelenium Dependent TrxRValeric AcidGlutathione PeroxidaseThioredoxin ReductaseSelenium Dependent Selenoproteins

Ecological state

1 shared

Shared

SCFA Depletion

Only in Long COVID

Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBarrier DysfunctionBacterial TranslocationMulti Kingdom Co DysbiosisNon Linear Recovery

Only in Hashimoto's Thyroiditis

Molecular MimicryIodine Driven DysbiosisTh17 Treg ImbalanceTryptophan Metabolism DisruptionBile Acid DysmetabolismButyrate DepletionOxidative Stress

Virulence and functional enzymes

1 shared

Shared

Beta-Glucuronidase

Only in Long COVID

LPS Synthesis TransportSiderophoresAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Polysaccharide DegradationLPS Biosynthesis EnzymesBeta Lactamases

Only in Hashimoto's Thyroiditis

Bacterial DeiodinasesLPS EndotoxinIDO1 Kynurenine AhR PathwayThyroid Peroxidase Mimics