Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
14: shared signals

First condition

Second condition

Comparison

Hashimoto's ThyroiditisandLong COVID

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

17: Hashimoto's Thyroiditis references
18: Long COVID references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Hashimoto's Thyroiditis

Iodine ExcessCadmium Lead Mercury Nickel Copper

Only in Long COVID

Zinc Arsenic Thallium

Metals depleted or redistributed

2 shared

Taxa enriched

1 shared

Shared

Klebsiella pneumoniae

Only in Hashimoto's Thyroiditis

Proteobacteria (Pseudomonadota)Actinobacteria (Actinomycetota)Blautia Dorea Prevotella Akkermansia muciniphila Bifidobacterium Intestinimonas Turicibacter

Only in Long COVID

Enterobacteriaceae Streptococcus Enterococcus Veillonella Candida albicans Fusobacterium nucleatum Aspergillus Escherichia coli

Taxa depleted

6 shared

Shared

Bifidobacterium Lactobacillus Faecalibacterium prausnitzii Akkermansia muciniphila Roseburia Lachnospiraceae

Only in Hashimoto's Thyroiditis

Coprococcus

Only in Long COVID

None indexed

Host response elevated

2 shared

Shared

Calprotectin (S100A8/A9)Hepcidin

Only in Hashimoto's Thyroiditis

CeruloplasminAdvanced Glycation End Products

Only in Long COVID

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)IFN-gamma (Interferon Gamma)LPS In CirculationPD 1 On CD8TIM 3 On CD8AutoantibodiesZinc In Secretions

Host response depleted

1 shared

Shared

Butyrate

Only in Hashimoto's Thyroiditis

Selenium Dependent GPxSelenium Dependent TrxRValeric AcidGlutathione PeroxidaseThioredoxin ReductaseSelenium Dependent Selenoproteins

Only in Long COVID

Regulatory T CellsNK Cell FunctionMemory B CellsSIgAGlutathione (GSH)SeleniumIron In Tissues

Ecological state

1 shared

Shared

SCFA Depletion

Only in Hashimoto's Thyroiditis

Molecular MimicryIodine Driven DysbiosisTh17 Treg ImbalanceTryptophan Metabolism DisruptionBile Acid DysmetabolismButyrate DepletionOxidative Stress

Only in Long COVID

Self Perpetuating Dysbiosis LoopAnaerobe To Aerobe ShiftSCFA CollapseBacterial Translocation EndotoxemiaGut Lung Axis DisruptionGut Brain Axis DisruptionTryptophan AhR DysmetabolismVirome Co DysbiosisMulti Kingdom DysbiosisNon Linear Recovery TrajectoryStrain Level Diversity CollapseEstrobolome DysfunctionUremic Metabolite AccumulationHypoxia CellularAerobe BloomBarrier DysfunctionBacterial TranslocationMulti Kingdom Co DysbiosisNon Linear Recovery

Virulence and functional enzymes

1 shared

Shared

Beta-Glucuronidase

Only in Hashimoto's Thyroiditis

Bacterial DeiodinasesLPS EndotoxinIDO1 Kynurenine AhR PathwayThyroid Peroxidase Mimics

Only in Long COVID

LPS Synthesis TransportSiderophoresAdhesion Invasion FactorsBile Salt Hydrolase (BSH)Polysaccharide DegradationLPS Biosynthesis EnzymesBeta Lactamases