Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 12%
- weighted overlap
- 9
- shared signals
Comparison
DepressionandEpilepsy
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Depression references
- 9
- Epilepsy references
- 0
- shared references
Metals depleted or redistributed
3 sharedTaxa enriched
0 sharedShared
None indexed
Only in Depression
Only in Epilepsy
Taxa depleted
1 sharedShared
Only in Depression
Only in Epilepsy
Host response elevated
1 sharedShared
Only in Depression
Only in Epilepsy
Host response depleted
0 sharedShared
None indexed
Only in Depression
Only in Epilepsy
Ecological state
2 sharedShared
SCFA DepletionNeuroinflammation
Only in Depression
DysbiosisLeaky GutIntestinal PermeabilityEndotoxemiaLow SCFA ProductionImpaired Tryptophan MetabolismReduced Indole ProductionHPA Axis DysregulationTryptophan Shunting IDOHPA Axis HyperactivationBlood Brain Barrier Disruption
Only in Epilepsy
Oral Gut TranslocationMucin DegradationKynurenine Pathway Shunting
Virulence and functional enzymes
1 sharedShared
Tryptophanase
Only in Depression
Beta-GlucuronidaseLPS BiosynthesisPro Inflammatory Metabolite SynthesisBiofilm Formation EnzymesIndoleamine 2 3 Dioxygenase IDOBacterial TryptophanaseLPS Biosynthesis EnzymesBacterial Amyloids Curli
Only in Epilepsy
Beta GlucosidaseIndoleamine 2 3 Dioxygenase Upregulation