Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 22%
- weighted overlap
- 24
- shared signals
Comparison
Crohn's DiseaseandColorectal Cancer
0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 25
- Crohn's Disease references
- 36
- Colorectal Cancer references
- 0
- shared references
Metals depleted or redistributed
3 sharedShared
Only in Crohn's Disease
Only in Colorectal Cancer
Taxa enriched
4 sharedShared
Only in Crohn's Disease
Only in Colorectal Cancer
Taxa depleted
4 sharedShared
Only in Crohn's Disease
Only in Colorectal Cancer
Host response elevated
3 sharedShared
Only in Crohn's Disease
Only in Colorectal Cancer
Host response depleted
1 sharedShared
Only in Crohn's Disease
Anti Inflammatory CytokinesAlpha Defensins
Only in Colorectal Cancer
Ecological state
3 sharedShared
Only in Crohn's Disease
Barrier DysfunctionLeaky GutBile Acid DysmetabolismTryptophan DepletionFermentative MetabolismFerroptosisButyrate CollapseNOD2 Paneth Cell Defect
Only in Colorectal Cancer
Secondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessWarburg EffectCross Kingdom DysbiosisVirome Network Disruption
Virulence and functional enzymes
1 sharedShared
Only in Crohn's Disease
Zinc-MetalloproteaseIron Dependent HydrogenaseCobalt Dependent EnzymesCopper Resistance DeterminantsMucin Degrading EnzymesSiderophores EnterobactinSiderophores YersiniabactinSiderophores AerobactinZinc Metalloprotease BFTFimH AdhesinOuter Membrane VesiclesNickel-Urease
Only in Colorectal Cancer
FadAFap2LPS TLR4BFT ToxinColibactin PksUreaseGlyoxalase IBeta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase