Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

15%: weighted overlap
13: shared signals

First condition

Second condition

Comparison

Colorectal CancerandRheumatoid Arthritis

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

36: Colorectal Cancer references
7: Rheumatoid Arthritis references
0: shared references

Metals elevated or accumulated

5 shared

Shared

Cadmium Lead Copper Arsenic Chromium

Only in Colorectal Cancer

Iron Zinc Nickel

Only in Rheumatoid Arthritis

None indexed

Metals depleted or redistributed

0 shared

Shared

None indexed

Only in Colorectal Cancer

Butyrate Zinc Selenium Manganese

Only in Rheumatoid Arthritis

Vitamin D Nickel

Taxa enriched

1 shared

Taxa depleted

3 shared

Shared

Lachnospiraceae Faecalibacterium prausnitzii Bifidobacterium

Only in Colorectal Cancer

Roseburia Prevotella copri Ruminococcus albus Dialister Lactobacillus Ruminococcus

Only in Rheumatoid Arthritis

Bacteroides fragilis

Host response elevated

2 shared

Shared

Calprotectin (S100A8/A9)Hepcidin

Only in Colorectal Cancer

IL 6TNF-alpha (Tumor Necrosis Factor Alpha)IL-1beta (Interleukin-1 Beta)Lipopolysaccharide Lipocalin-2

Only in Rheumatoid Arthritis

Ceruloplasmin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Colorectal Cancer

IL-10 (Interleukin-10)IgATreg CellsSelenium Dependent Glutathione Peroxidase

Only in Rheumatoid Arthritis

Vitamin D

Ecological state

0 shared

Shared

None indexed

Only in Colorectal Cancer

Hypoxia BiofilmSecondary Bile Acid AccumulationFermentative Acidic MicroenvironmentEpithelial Barrier DisruptionColonic Serotonin DepletionAnaerobic DominanceSecondary Bile Acid ExcessSCFA DepletionWarburg EffectCross Kingdom DysbiosisVirome Network Disruption

Only in Rheumatoid Arthritis

Mucosal Origin AutoimmunityBarrier DysfunctionMolecular MimicryTh17 DominanceMetal VitD Bone AxisSoil Food Chain Exposure

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Colorectal Cancer

FadAFap2LPS TLR4BFT ToxinColibactin PksUrease Glyoxalase I Beta-GlucuronidaseBFT Zinc MetalloproteaseColibactin GenotoxinFadA AdhesinFap2 LectinNAD(P)H Oxidase

Only in Rheumatoid Arthritis

MetalloproteinasesLPS Biosynthesis Enzymes