Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

21%: weighted overlap
18: shared signals

First condition

Second condition

Comparison

Cerebral PalsyandType 2 Diabetes

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

9: Cerebral Palsy references
30: Type 2 Diabetes references
0: shared references

Metals elevated or accumulated

2 shared

Metals depleted or redistributed

1 shared

Shared

Zinc

Only in Cerebral Palsy

Iron

Only in Type 2 Diabetes

Chromium Magnesium Glutathione (GSH)Manganese

Taxa enriched

3 shared

Shared

Streptococcus Enterococcus Prevotella

Only in Cerebral Palsy

Akkermansia muciniphila Veillonella Klebsiella Klebsiella pneumoniae Fusobacterium

Only in Type 2 Diabetes

Escherichia coli Enterobacteriaceae Candida albicans Helicobacter pylori Campylobacter jejuni

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Blautia Ruminococcus Roseburia Bacteroides fragilis

Only in Cerebral Palsy

Bacteroides Lactobacillus

Only in Type 2 Diabetes

Bifidobacterium Akkermansia muciniphila Lachnospiraceae

Host response elevated

3 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)IL 6Hepcidin

Only in Cerebral Palsy

Pro Inflammatory CytokinesIL-1beta (Interleukin-1 Beta)Calprotectin (S100A8/A9)IL-8 (Interleukin-8 / CXCL8)IL-10 (Interleukin-10)

Only in Type 2 Diabetes

LipopolysaccharideInflammatory CytokinesFerritin Ceruloplasmin

Host response depleted

2 shared

Shared

Zinc Butyrate

Only in Cerebral Palsy

Iron Vitamin D

Only in Type 2 Diabetes

PropionateAcetateBile AcidsGlutathione (GSH)Chromium Manganese Magnesium

Ecological state

1 shared

Shared

SCFA Depletion

Only in Cerebral Palsy

NEC To CP PathwayTLR4 LPS Microglial ActivationOral Gut Inflammatory AxisWhite Matter InjuryProteobacteria BloomKynurenine Pathway DysregulationOral Gut TranslocationMucin DegradationConstipation Driven Oxygen ShiftBiofilm

Only in Type 2 Diabetes

DysbiosisLPS ElevationBile Acid DysmetabolismImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth

Virulence and functional enzymes

1 shared

Shared

Siderophores

Only in Cerebral Palsy

LPS BiosynthesisTryptophanaseTLR4 LPS SignalingBeta Glucosidase

Only in Type 2 Diabetes

LipopolysaccharideCholine TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesLPS Biosynthesis EnzymesNickel-UreaseTMA Lyase CutC CutD