Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

12%: weighted overlap
10: shared signals

First condition

Second condition

Comparison

Breast CancerandType 2 Diabetes

1 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

21: Breast Cancer references
30: Type 2 Diabetes references
1: shared references

Metals elevated or accumulated

2 shared

Metals depleted or redistributed

2 shared

Shared

Zinc Manganese

Only in Breast Cancer

Selenium

Only in Type 2 Diabetes

Chromium Magnesium Glutathione (GSH)

Taxa enriched

0 shared

Shared

None indexed

Only in Breast Cancer

Fusobacterium nucleatum Bacteroides fragilis Acidaminococcus Hungatella Tyzzerella Klebsiella pneumoniae

Only in Type 2 Diabetes

Escherichia coli Enterobacteriaceae Streptococcus Prevotella Enterococcus Candida albicans Helicobacter pylori Campylobacter jejuni

Taxa depleted

2 shared

Shared

Bifidobacterium Akkermansia muciniphila

Only in Breast Cancer

Christensenellaceae Oscillospirales Dialister

Only in Type 2 Diabetes

Faecalibacterium prausnitzii Lachnospiraceae Ruminococcus Bacteroides fragilis Roseburia Blautia

Host response elevated

2 shared

Shared

Ceruloplasmin Hepcidin

Only in Breast Cancer

Metallothionein

Only in Type 2 Diabetes

LipopolysaccharideInflammatory CytokinesTNF-alpha (Tumor Necrosis Factor Alpha)IL 6Ferritin

Host response depleted

1 shared

Shared

Glutathione (GSH)

Only in Breast Cancer

Glutathione PeroxidaseCu Zn SODMnSOD

Only in Type 2 Diabetes

ButyratePropionateAcetateBile AcidsZinc Chromium Manganese Magnesium

Ecological state

1 shared

Shared

SCFA Depletion

Only in Breast Cancer

Estrogen RecirculationBeta Glucuronidase ActivityMetalloestrogen BurdenAlpha Diversity ReductionCross Kingdom Dysbiosis

Only in Type 2 Diabetes

DysbiosisLPS ElevationBile Acid DysmetabolismImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth

Virulence and functional enzymes

0 shared

Shared

None indexed

Only in Breast Cancer

Beta-GlucuronidaseBFT Zinc MetalloproteaseFadA AdhesinFap2 LectinMMP 9

Only in Type 2 Diabetes

LipopolysaccharideCholine TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesSiderophoresLPS Biosynthesis EnzymesNickel-UreaseTMA Lyase CutC CutD