Comparative evidence

Compare conditions

Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.

18%: weighted overlap
13: shared signals

First condition

Second condition

Comparison

Type 2 DiabetesandAnxiety Disorders

0 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.

30: Type 2 Diabetes references
12: Anxiety Disorders references
0: shared references

Metals elevated or accumulated

0 shared

Shared

None indexed

Only in Type 2 Diabetes

Iron Nickel Cadmium Arsenic Lead

Only in Anxiety Disorders

Copper

Metals depleted or redistributed

2 shared

Taxa enriched

1 shared

Shared

Escherichia coli

Only in Type 2 Diabetes

Enterobacteriaceae Streptococcus Prevotella Enterococcus Candida albicans Helicobacter pylori Campylobacter jejuni

Only in Anxiety Disorders

Collinsella Prevotellaceae

Taxa depleted

5 shared

Shared

Faecalibacterium prausnitzii Bifidobacterium Lachnospiraceae Roseburia Blautia

Only in Type 2 Diabetes

Akkermansia muciniphila Ruminococcus Bacteroides fragilis

Only in Anxiety Disorders

Lactobacillus

Host response elevated

2 shared

Shared

TNF-alpha (Tumor Necrosis Factor Alpha)IL 6

Only in Type 2 Diabetes

Lipopolysaccharide HepcidinInflammatory CytokinesFerritin Ceruloplasmin

Only in Anxiety Disorders

Cortisol IL-1beta (Interleukin-1 Beta)CRP

Host response depleted

1 shared

Shared

Butyrate

Only in Type 2 Diabetes

PropionateAcetateBile AcidsGlutathione (GSH)Zinc Chromium Manganese Magnesium

Only in Anxiety Disorders

Serotonin GABA (Gamma-Aminobutyric Acid)BDNF (Brain-Derived Neurotrophic Factor)

Ecological state

1 shared

Shared

SCFA Depletion

Only in Type 2 Diabetes

DysbiosisLPS ElevationBile Acid DysmetabolismImpaired Intestinal BarrierLipid PeroxidationReduced Microbial DiversityEndotoxemiaGut Barrier DisruptionBile Acid DysregulationIron Overload Oxidative StressFungal Overgrowth

Only in Anxiety Disorders

Tryptophan Kynurenine ShuntingHPA Axis DysregulationVagal Signaling DisruptionGut Barrier Dysfunction

Virulence and functional enzymes

1 shared

Shared

LPS Biosynthesis Enzymes

Only in Type 2 Diabetes

LipopolysaccharideCholine TMA LyaseBile Acid DehydrataseCarbohydrate Fermentation EnzymesSiderophores Nickel-UreaseTMA Lyase CutC CutD

Only in Anxiety Disorders

Indoleamine 2 3 DioxygenaseTryptophanase