Comparative evidence
Compare conditions
Put two canonical disease records side by side. The result is a shareable, deterministic comparison of what is shared, what is unique, and how much evidence each record currently carries.
- 24%
- weighted overlap
- 23
- shared signals
Comparison
Parkinson's DiseaseandObesity
3 references occur in both reconciled evidence sets. Shared signals do not establish shared causes, diagnoses, or treatments.
- 38
- Parkinson's Disease references
- 31
- Obesity references
- 3
- shared references
Metals depleted or redistributed
1 sharedTaxa enriched
2 sharedShared
Only in Parkinson's Disease
Only in Obesity
Taxa depleted
3 sharedShared
Only in Parkinson's Disease
Only in Obesity
Host response elevated
5 sharedShared
Only in Parkinson's Disease
Inflammatory Cytokines TNF IL6 IL1betaTransferrin Receptor Altered
Only in Obesity
Host response depleted
2 sharedShared
Only in Parkinson's Disease
Only in Obesity
Ecological state
2 sharedShared
Only in Parkinson's Disease
Iron Rich MicroenvironmentFunctional ShieldingBacterial TranslocationGut PermeabilityDysbiotic FermentationFerroptosisAlpha Synuclein Gut SeedingBlood Brain Barrier DisruptionLPS EndotoxemiaSCFA DepletionVagal Nerve PropagationHypoxia GutSiderophore Competition
Only in Obesity
Metal Driven DysbiosisReduced SCFA ProductionIncreased LPSEndotoxemiaIntestinal Permeability IncreaseFermentative MetabolismMetabolic EndotoxemiaReduced Microbial DiversityIncreased Energy HarvestBile Acid DysregulationVirome Depletion
Virulence and functional enzymes
3 sharedShared
Only in Parkinson's Disease
Iron SiderophoresZinc-MetalloproteaseMucinaseLipopolysaccharide LPSBacterial Amyloids CurliNiFe-HydrogenaseCurli AmyloidLPS